SPATA18 抗体 (AA 27-490)
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- 抗原 See all SPATA18 抗体
- SPATA18 (Spermatogenesis Associated 18 (SPATA18))
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抗原表位
- AA 27-490
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPATA18 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 原理
- Anti-SPATA18 Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-SPATA18 Antibody Picoband® (ABIN7601020). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human SPATA18 recombinant protein (Position: E27-R490).
- 亚型
- IgG
- Top Product
- Discover our top product SPATA18 Primary Antibody
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anti-Spermatogenesis Associated 18 (SPATA18) antibody
SPATA18 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spermatogenesis Associated 18 (SPATA18) (AA 92-120), (N-Term) antibodySPATA18 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB27204 unconjugated
anti-Spermatogenesis Associated 18 (SPATA18) (N-Term) antibodySPATA18 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鸡 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bornstein, C., Brosh, R., Molchadsky, A., Madar, S., Kogan-Sakin, I., Goldstein, I., Chakravarti, D., Flores, E. R., Goldfinger, N., Sarig, R., Rotter, V. SPATA18, a spermatogenesis-associated gene, is a novel transcriptional target of p53 and p63. Molec. Cell. Biol. 31: 1679-1689, 2011. 2. Iida, H., Ichinose, J., Kaneko, T., Mori, T., Shibata, Y. Complementary DNA cloning of rat Spetex-1, a spermatid-expressing gene-1, encoding a 63 kDa cytoplasmic protein of elongate spermatids. Molec. Reprod. Dev. 68: 385-393, 2004. 3. Kaindl, A. M., Jakubiczka, S., Lucke, T., Bartsch, O., Weis, J., Stoltenburg-Didinger, G., Aksu, F., Oexle, K., Koehler, K., Huebner, A. Homozygous microdeletion of chromosome 4q11-q12 causes severe limb-girdle muscular dystrophy type 2E with joint hyperlaxity and contractures. (Abstract) Hum. Mutat. 26: 279-280, 2005. Note: Full article online. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- SPATA18 (Spermatogenesis Associated 18 (SPATA18))
- 别名
- SPATA18 (SPATA18 产品)
- 背景
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Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6
Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.
Background: This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants.
- 分子量
- 61 kDa
- 基因ID
- 132671
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