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KLHL12 抗体 (AA 27-331)

The 小鼠 单克隆 anti-KLHL12 antibody is suitable to detect KLHL12 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 IHC.
产品编号 ABIN7601008
发货至: 中国
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Quick Overview for KLHL12 抗体 (AA 27-331) (ABIN7601008)

抗原

See all KLHL12 抗体
KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

适用

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  • 1
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人, 小鼠, 大鼠

宿主

  • 46
  • 4
小鼠

克隆类型

  • 47
  • 3
单克隆

标记

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  • 4
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  • 3
  • 1
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This KLHL12 antibody is un-conjugated

应用范围

  • 37
  • 17
  • 13
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  • 4
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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

2G11D1
  • 抗原表位

    • 15
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    AA 27-331

    原理

    Anti-KLHL12 Antibody (monoclonal, 2G11D1)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-KLHL12 Antibody (monoclonal, 2G11D1) (ABIN7601008). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human KLHL12 recombinant protein (Position: R27-I331).

    亚型

    IgG2a
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

    别名

    KLHL12

    背景

    Synonyms: T-complex protein 1 subunit gamma, TCP-1-gamma, CCT-gamma, hTRiC5, CCT3, CCTG, TRIC5

    Tissue Specificity: Ubiquitously expressed with highest levels in spleen, thymus and immature brain.

    Background: Kelch-like protein 12 is a protein that in humans is encoded by the KLHL12 gene. This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants.

    分子量

    63 kDa

    基因ID

    59349

    UniProt

    Q53G59
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