KLHL12 抗体 (AA 27-331)
Quick Overview for KLHL12 抗体 (AA 27-331) (ABIN7601008)
抗原
See all KLHL12 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 27-331
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原理
- Anti-KLHL12 Antibody Picoband® (monoclonal, 2G11D1)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-KLHL12 Antibody Picoband® (monoclonal, 2G11D1) (ABIN7601008). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human KLHL12 recombinant protein (Position: R27-I331).
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亚型
- IgG2a
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anti-Kelch-Like 12 (Drosophila) (KLHL12) (AA 1-220) antibody
KLHL12 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) antibodyKLHL12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) (N-Term) antibodyKLHL12 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) (AA 81-341) antibodyKLHL12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) (N-Term) antibodyKLHL12 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) (AA 376-404), (C-Term) antibodyKLHL12 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB37184 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
1. Hartz, P. A. Personal Communication. Baltimore, Md. 3/7/2012. 2. Jin, L., Pahuja, K. B., Wickliffe, K. E., Gorur, A., Baumgartel, C., Schekman, R., Rape, M. Ubiquitin-dependent regulation of COPII coat size and function. Nature 482: 495-500, 2012. 3. Mai, A., Jung, S.-K., Yonehara, S. hDKIR, a human homologue of the Drosophila kelch protein, involved in a ring-like structure. Exp. Cell Res. 300: 72-83, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
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别名
- KLHL12
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背景
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Synonyms: T-complex protein 1 subunit gamma, TCP-1-gamma, CCT-gamma, hTRiC5, CCT3, CCTG, TRIC5
Tissue Specificity: Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Background: Kelch-like protein 12 is a protein that in humans is encoded by the KLHL12 gene. This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants.
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分子量
- 63 kDa
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基因ID
- 59349
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UniProt
- Q53G59
抗原
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