SURF1 抗体 (AA 27-295)
Quick Overview for SURF1 抗体 (AA 27-295) (ABIN7601006)
抗原
See all SURF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-295
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原理
- Anti-SURF1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SURF1 Antibody Picoband® (ABIN7601006). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SURF1 recombinant protein (Position: S27-R295).
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亚型
- IgG
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anti-Surfeit 1 (SURF1) (Internal Region) antibody
SURF1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Surfeit 1 (SURF1) (Internal Region) antibodySURF1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Surfeit 1 (SURF1) (Internal Region) antibodySURF1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Surfeit 1 (SURF1) (AA 80-275) antibodySURF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Surfeit 1 (SURF1) (Center) antibodySURF1 适用: 人, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Surfeit 1 (SURF1) (AA 171-220) antibodySURF1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Surfeit 1 (SURF1) (AA 1-300) antibodySURF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Surfeit 1 (SURF1) (N-Term) antibodySURF1 适用: 人, Cow, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Surfeit 1 (SURF1) (N-Term) antibodySURF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Surfeit 1 (SURF1) (Internal Region) antibodySURF1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Agostino, A., Invernizzi, F., Tiveron, C., Fagiolari, G., Prelle, A., Lamantea, E., Giavazzi, A., Battaglia, G., Tatangelo, L., Tiranti, V., Zeviani, M. Constitutive knockout of Surf1 is associated with high embryonic lethality, mitochondrial disease and cytochrome c oxidase deficiency in mice. Hum. Molec. Genet. 12: 399-413, 2003. 2. Bohm, M., Pronicka, E., Karczmarewicz, E., Pronicki, M., Piekutowska-Abramczuk, D., Sykut-Cegielska, J., Mierzewska, H., Hansikova, H., Vesela, K., Tesarova, M., Houstkova, H., Houstek, J., Zeman, J. Retrospective, multicentric study of 180 children with cytochrome c oxidase deficiency. Pediat. Res. 59: 21-26, 2006. 3. Colombo, P., Yon, J., Garson, K., Fried, M. Conservation of the organization of five tightly clustered genes over 600 million years of divergent evolution. Proc. Nat. Acad. Sci. 89: 6358-6362, 1992. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SURF1 (Surfeit 1 (SURF1))
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别名
- SURF1
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背景
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Synonyms: p-selectin glycoprotein ligand, Selplg, Psgl1
Tissue Specificity: Highly expressed in blood, bone marrow, brain, adipose tissue, spleen, and thymus. Also expressed in heart, kidney, liver, muscle, ovary, and stomach.
Background: Surfeit locus protein 1 (SURF1) is a protein that in humans is encoded by the SURF1 gene. This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a biional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
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分子量
- 33 kDa
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基因ID
- 6834
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UniProt
- Q15526
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途径
- Proton Transport, Ribonucleoside Biosynthetic Process
抗原
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