Azurocidin 抗体 (AA 27-245)
Quick Overview for Azurocidin 抗体 (AA 27-245) (ABIN7601000)
抗原
See all Azurocidin (AZU1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-245
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原理
- Anti-Azurocidin/AZU1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Azurocidin/AZU1 Antibody Picoband® (ABIN7601000). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Azurocidin/AZU1 recombinant protein (Position: I27-N245).
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亚型
- IgG
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anti-Azurocidin 1 (AZU1) (AA 23-247) antibody
AZU1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Azurocidin 1 (AZU1) (AA 1-251) antibodyAZU1 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-Azurocidin 1 (AZU1) (AA 27-251) antibodyAZU1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Azurocidin 1 (AZU1) (AA 23-247) antibodyAZU1 适用: 人 WB 宿主: 小鼠 Monoclonal D1 unconjugated
anti-Azurocidin 1 (AZU1) (AA 27-251) antibodyAZU1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Azurocidin 1 (AZU1) (AA 66-96), (Middle Region) antibodyAZU1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-Azurocidin 1 (AZU1) (AA 67-96) antibodyAZU1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Morgan, J. G. , Sukiennicki, T. , Pereira, H. A. , Spitznagel, J. K. , & Larrick, J. W. . (1991). Cloning of the cdna for the serine protease homolog cap37/azurocidin, a microbicidal and chemotactic protein from human granulocytes. The Journal of Immunology, 147(9), 3210-3214. 2. M, Zimmer, R, L, Medcalf, & T, et al. (1992). Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter. Proceedings of the National Academy of Sciences of the United States of America. 3. Gautam, N. , Olofsson, A. M. , Herwald, H. , Iversen, L. F. , & Lindbom, L. . (2001). Heparin-binding protein (hbp/cap37): a missing link in neutrophil-evoked alteration of vascular permeability. Nature Medicine, 7(10), 1123. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Azurocidin (AZU1) (Azurocidin 1 (AZU1))
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别名
- AZU1
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背景
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Synonyms: Mucin-7, MUC-7, Apo-MG2, Salivary mucin-7, MUC7, MG2
Tissue Specificity: Expressed in salivary gland tissues and only in those that contain mucous acinar cells (e.g. sublingual and submandibular glands) and not in salivary glands containing only serous acinar cells (e.g. parotid gland).
Background: Azurocidin also known as cationic antimicrobial protein CAP37 or heparin-binding protein (HBP) is a protein that in humans is encoded by the AZU1 gene. Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
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分子量
- 37 kDa
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基因ID
- 566
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UniProt
- P20160
抗原
-
