EVL 抗体 (AA 268-400)
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- 抗原 See all EVL 抗体
- EVL (Ena-Vasodilator Stimulated Phosphoprotein (EVL))
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抗原表位
- AA 268-400
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EVL antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 原理
- Anti-EVL Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-EVL Antibody Picoband® (ABIN7600986). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human EVL recombinant protein (Position: M268-E400).
- 亚型
- IgG
- Top Product
- Discover our top product EVL Primary Antibody
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anti-Ena-Vasodilator Stimulated Phosphoprotein (EVL) (AA 309-418) antibody
EVL 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5G1 unconjugated
anti-Ena-Vasodilator Stimulated Phosphoprotein (EVL) (AA 309-418) antibodyEVL 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ena-Vasodilator Stimulated Phosphoprotein (EVL) (Internal Region) antibodyEVL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ena-Vasodilator Stimulated Phosphoprotein (EVL) (Middle Region) antibodyEVL 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 4/19/2016. 2. Janssens, K., De Kimpe, L., Balsamo, M., Vandoninck, S., Vandenheede, J. R., Gertler, F., Van Lint, J. Characterization of EVL-I as a protein kinase D substrate. Cell. Signal. 21: 282-292, 2009. 3. Klostermann, A., Lutz, B., Gertler, F., Behl, C. The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxyl-terminal zyxin-like domain. J. Biol. Chem. 275: 39647-39653, 2000. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- EVL (Ena-Vasodilator Stimulated Phosphoprotein (EVL))
- 别名
- EVL (EVL 产品)
- 背景
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Synonyms: Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, CD252, Tnfsf4, Ox40l, Txgp1l
Tissue Specificity: Macrophages, peripheral blood leukocytes, lung, spleen and liver.
Background: Ena/VASP-like protein is a member of the Ena/VASP family of proteins that in humans is encoded by the EVL gene. Ena/VASP-like (EVL) protein is a member of the Ena/VASP family and is involved in actin-associated cytoskeleton remodeling and cell polarity activities including axon guidance and lamellipodia formation in migrating cells. The EVL protein sequence contains an N-terminal EVH1 domain, a Pro-rich SH3 binding domain, and a C-terminal EVH2 domain. EVL domain interactions with G- and F-actin mediates actin nucleation and polymerization. Research studies have shown that EVL also regulates DNA repair by interaction with RAD51. EVL may function in the DSB repair pathway through the EVH2 domain, which possesses DNA-binding and RAD51 binding activity, thereby coordinating homologous DNA recombination. Research studies have shown EVL expression is up-regulated in human breast cancer associated with clinical stages and may be implicated in invasion and/or metastasis of human breast cancer.
- 分子量
- 50 kDa
- 基因ID
- 51466
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