Shroom Family Member 4 (SHROOM4) (AA 262-928) 抗体
Quick Overview for Shroom Family Member 4 (SHROOM4) (AA 262-928) 抗体 (ABIN7600980)
抗原
适用
宿主
克隆类型
应用范围
-
-
抗原表位
- AA 262-928
-
原理
- Anti-SHROOM4 Antibody Picoband®
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
产品特性
- Anti-SHROOM4 Antibody Picoband® (ABIN7600980). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SHROOM4 recombinant protein (Position: Y262-H928).
-
亚型
- IgG
-
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hagens, O., Dubos, A., Abidi, F., Barbi, G., Van Zutven, L., Hoeltzenbein, M., Tommerup, N., Moraine, C., Fryns, J.-P., Chelly, J., van Bokhoven, H., Gecz, J., Dollfus, H., Ropers, H.-H., Schwartz, C. E., Stocco dos Santos, R. C., Kalscheuer, V., Hanauer, A. Disruptions of the novel KIAA1202 gene are associated with X-linked mental retardation. Hum. Genet. 118: 578-590, 2006. 2. Lopes, F., Barbosa, M., Ameur, A., Soares, G., de Sa, J., Dias, A. I., Oliveira, G., Cabral, P., Temudo, T., Calado, E., Cruz, I. F., Vieira, J. P., Oliveira, R., Esteves, S., Sauer, S., Jonasson, I., Syvanen, A.-C., Gyllensten, U., Pinto, D., Maciel, P. Identification of novel genetic causes of Rett syndrome-like phenotypes. J. Med. Genet. 53: 190-199, 2016. 3. Nagase, T., Ishikawa, K., Kikuno, R., Hirosawa, M., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 6: 337-345, 1999. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- Shroom Family Member 4 (SHROOM4)
-
别名
- SHROOM4
-
背景
-
Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7
Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.
Background: This gene encodes a member of the APX/Shroom family, which contain an N-terminal PDZ domain and a C-terminal ASD2 motif. The encoded protein may play a role in cytoskeletal architecture. Mutations in this gene have been linked to the X-linked Stocco dos Santos syndrome characterized by cognitive disabilities. Alternatively spliced transcript variants have been described.
-
分子量
- 170-180 kDa
-
基因ID
- 57477
抗原
-