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NAD-ME 抗体 (AA 26-584)

This anti-NAD-ME antibody is a 兔 多克隆 antibody detecting NAD-ME in WB, ELISA, IHC, IF, ICC 和 FACS. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7600967
发货至: 中国

Quick Overview for NAD-ME 抗体 (AA 26-584) (ABIN7600967)

抗原

See all NAD-ME 抗体
NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This NAD-ME antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 26-584

    原理

    Anti-ME2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-ME2 Antibody Picoband® (ABIN7600967). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ME2 recombinant protein (Position: K26-E584).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Monkey, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    Immunofluorescence, 2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Burchell, A., Crosby, A., Cohen, P. T. W. Human mitochondrial malic enzyme variants: properties of the different polymorphic forms. Ann. Hum. Genet. 41: 1-7, 1977. 2. Champion, M. J., Brown, J. A., Shows, T. B. Assignment of cytoplasmic alpha-mannosidase (MAN-A) and confirmation of mitochondrial isocitrate dehydrogenase (IDH-M) to the q11-qter region of chromosome 15 in man. Cytogenet. Cell Genet. 22: 498-502, 1978. 3. Cohen, P. T. W., Omenn, G. S. Genetic variation of the cytoplasmic and mitochondrial malic enzymes in the monkey: Macaca nemestrina. Biochem. Genet. 7: 289-301, 1972.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

    别名

    ME2

    背景

    Synonyms: NAD-dependent malic enzyme, mitochondrial, NAD-ME, Malic enzyme 2, ME2

    Tissue Specificity: Ubiquitous. Highly expressed in testis.

    Background: NAD-dependent malic enzyme, mitochondrial is a protein that in humans is encoded by the ME2 gene. It is mapped to 18q21.2. This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

    分子量

    65 kDa

    基因ID

    4200

    UniProt

    P23368

    途径

    Production of Molecular Mediator of Immune Response
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