TGIF1 抗体 (AA 26-401)
Quick Overview for TGIF1 抗体 (AA 26-401) (ABIN7600959)
抗原
See all TGIF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-401
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原理
- Anti-TGIF/TGIF1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TGIF/TGIF1 Antibody Picoband® (ABIN7600959). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TGIF/TGIF1 recombinant protein (Position: D26-A401).
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亚型
- IgG
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anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 8-375) antibody
TGIF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (C-Term) antibodyTGIF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 163-272) antibodyTGIF1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 163-272) antibodyTGIF1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 324-373) antibodyTGIF1 适用: 人, 小鼠, 大鼠, 马, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 123-272) antibodyTGIF1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 208-237) antibodyTGIF1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB14110 unconjugated
anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (AA 215-245), (Middle Region) antibodyTGIF1 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Aguilella, C., Dubourg, C., Attia-Sobol, J., Vigneron, J., Blayau, M., Pasquier, L., Lazaro, L., Odent, S., David, V. Molecular screening of the TGIF gene in holoprosencephaly: identification of two novel mutations. Hum. Genet. 112: 131-134, 2003. 2. Bertolino, E., Reimund, B., Wildt-Perinic, D., Clerc, R. G. A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif. J. Biol. Chem. 270: 31178-31188, 1995. 3. Bertolino, E., Wildt, S., Richards, G., Clerc, R. G. Expression of a novel murine homeobox gene in the developing cerebellar external granular layer during its proliferation. Dev. Dyn. 205: 410-420, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
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别名
- TGIF1
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背景
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Synonyms: Olfactomedin-4, OLM4, Antiapoptotic protein GW112, G-CSF-stimulated clone 1 protein, hGC-1, hOLfD, OLFM4, GW112, UNQ362, PRO698
Tissue Specificity: Expressed during myeloid lineage development. Much higher expression in bone marrow neutrophils than in peripheral blood neutrophils (at protein level). Strongly expressed in the prostate, small intestine and colon and moderately expressed in the bone marrow and stomach. Overexpressed in some pancreatic cancer tissues.
Background: Homeobox protein TGIF1 is a protein that, in humans, is encoded by the TGIF1 gene. The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described.
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分子量
- 43 kDa
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基因ID
- 7050
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UniProt
- Q15583
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途径
- Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
抗原
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