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KMO 抗体 (AA 26-372)

This anti-KMO antibody is a 兔 多克隆 antibody detecting KMO in WB, ELISA, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7600958
发货至: 中国

Quick Overview for KMO 抗体 (AA 26-372) (ABIN7600958)

抗原

See all KMO 抗体
KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))

适用

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人, 小鼠, 大鼠

宿主

  • 37
  • 7
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克隆类型

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  • 5
多克隆

标记

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This KMO antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

    • 7
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    AA 26-372

    原理

    Anti-KMO Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-KMO Antibody Picoband® (ABIN7600958). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human KMO recombinant protein (Position: F26-N372).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse,Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. Alberati-Giani, D., Cesura, A. M., Broger, C., Warren, W. D., Rover, S., Malherbe, P. Cloning and functional expression of human kynurenine 3-monooxygenase. FEBS Lett. 410: 407-412, 1997. , 2. Giorgini, F., Guidetti, P., Nguyen, Q., Bennett, S. C., Muchowski, P. J. A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease. Nature Genet. 37: 526-536, 2005. 3. Halford, S., Freedman, M. S., Bellingham, J., Inglis, S. L., Poopalasundaram, S., Soni, B. G., Foster, R. G., Hunt, D. M. Characterization of a novel human opsin gene with wide tissue expression and identification of embedded and flanking genes on chromosome 1q43. Genomics 72: 203-208, 2001.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))

    别名

    KMO

    背景

    Synonyms: Prion-like protein doppel, PrPLP, Prion protein 2, PRND, DPL, UNQ1830/PRO3443

    Tissue Specificity: Expressed in testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid (at protein level).

    Background: Kynurenine 3-monooxygenase is an enzyme that in humans is encoded by the KMO gene. This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease.

    分子量

    50 kDa

    基因ID

    8564

    UniProt

    O15229
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