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SUMF2 抗体 (AA 26-301)

SUMF2 适用: 人 ELISA, WB, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7600954
发货至: 中国
  • 抗原 See all SUMF2 抗体
    SUMF2 (Sulfatase Modifying Factor 2 (SUMF2))
    抗原表位
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 26-301
    适用
    • 12
    • 3
    • 1
    宿主
    • 8
    • 4
    • 1
    克隆类型
    • 9
    • 4
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    This SUMF2 antibody is un-conjugated
    应用范围
    • 11
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    原理
    Anti-SUMF2 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-SUMF2 Antibody Picoband® (ABIN7600954). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human SUMF2 recombinant protein (Position: Q26-L301).
    亚型
    IgG
    Top Product
    Discover our top product SUMF2 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Cosma, M. P., Pepe, S., Annunziata, I., Newbold, R. F., Grompe, M., Parenti, G., Ballabio, A. The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases. Cell 113: 445-456, 2003. 2. Dierks, T., Schmidt, B., Borissenko, L. V., Peng, J., Preusser, A., Mariappan, M., von Figura, K. Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C-alpha-formylglycine generating enzyme. Cell 113: 435-444, 2003. 3. Gross, M. B. Personal Communication. Baltimore, Md. 2/26/2015.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    SUMF2 (Sulfatase Modifying Factor 2 (SUMF2))
    别名
    SUMF2 (SUMF2 产品)
    背景

    Synonyms: Pannexin-2, PANX2

    Tissue Specificity: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.

    Background: Sulfatase-modifying factor 2 is an enzyme that in humans is encoded by the SUMF2 gene. The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    分子量
    36 kDa
    基因ID
    25870
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