SUMF2 抗体 (AA 26-301)
Quick Overview for SUMF2 抗体 (AA 26-301) (ABIN7600954)
抗原
See all SUMF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-301
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原理
- Anti-SUMF2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SUMF2 Antibody Picoband® (ABIN7600954). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SUMF2 recombinant protein (Position: Q26-L301).
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亚型
- IgG
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anti-Sulfatase Modifying Factor 2 (SUMF2) (AA 26-125) antibody
SUMF2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4B3 unconjugated
anti-Sulfatase Modifying Factor 2 (SUMF2) (AA 26-301) antibodySUMF2 适用: 人 ELISA, WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sulfatase Modifying Factor 2 (SUMF2) (AA 26-125) antibodySUMF2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sulfatase Modifying Factor 2 (SUMF2) (AA 45-320) antibodySUMF2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cosma, M. P., Pepe, S., Annunziata, I., Newbold, R. F., Grompe, M., Parenti, G., Ballabio, A. The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases. Cell 113: 445-456, 2003. 2. Dierks, T., Schmidt, B., Borissenko, L. V., Peng, J., Preusser, A., Mariappan, M., von Figura, K. Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C-alpha-formylglycine generating enzyme. Cell 113: 435-444, 2003. 3. Gross, M. B. Personal Communication. Baltimore, Md. 2/26/2015. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SUMF2 (Sulfatase Modifying Factor 2 (SUMF2))
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别名
- SUMF2
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背景
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Synonyms: Pannexin-2, PANX2
Tissue Specificity: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.
Background: Sulfatase-modifying factor 2 is an enzyme that in humans is encoded by the SUMF2 gene. The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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分子量
- 36 kDa
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基因ID
- 25870
抗原
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