FGF15 抗体 (AA 26-218)
Quick Overview for FGF15 抗体 (AA 26-218) (ABIN7600946)
抗原
See all FGF15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-218
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原理
- Anti-Fgf19(Fgf15) Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Fgf19(Fgf15) Antibody Picoband® (ABIN7600946). Tested in IHC applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived rat Fgf19(Fgf15) recombinant protein (Position: R26-K218). Rat Fgf19(Fgf15) shares 53.2% and 96.4% amino acid (aa) sequence identity with human and mouse FGF19, respectively.
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亚型
- IgG
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anti-Fibroblast Growth Factor 15 (FGF15) (AA 25-218) antibody
FGF15 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 15 (FGF15) (AA 25-218) antibodyFGF15 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D3 unconjugated
anti-Fibroblast Growth Factor 15 (FGF15) (AA 26-218) antibodyFGF15 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
1. Jones, SA (2012). "Physiology of FGF15/19". Advances in Experimental Medicine and Biology. 728: 171-82. 2. Potthoff, MJ, Kliewer, SA, Mangelsdorf, DJ (2012). "Endocrine fibroblast growth factors 15/19 and 21: from feast to famine". Genes & Development. 26 (4): 312-324. 3. Owen, BM, Mangelsdorf, DJ, Kliewer, SA (January 2015). "Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21". Trends in Endocrinology and Metabolism. 26 (1): 22-9. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- FGF15 (Fibroblast Growth Factor 15 (FGF15))
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别名
- Fgf19(Fgf15)
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背景
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Synonyms: Fibroblast growth factor 19,FGF-19,FGF19,UNQ334/PRO533,
Tissue Specificity: Expressed in fetal brain, cartilage, retina, and adult gall bladder. .
Background: FGF15/19 refers to two orthologous fibroblast growth factors which share 50 % aminoacid identity and have similar functions. FGF15 was described in the mouse, FGF19 was found in humans and other species. They share physiological functions and so are often referred to as FGF15/19 or as FGF15/FGF19. They were first described in developing fetal brain. They are now known to be produced in the ileum, and under certain circumstances in the liver and biliary tree. It is thought their principal function is in response to bile acid absorption occurring after meals. FGF15 and FGF19 have similar roles in regulating bile acid synthesis and also glucose metabolism in the liver.
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分子量
- 24 kDa
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基因ID
- 170582, 14170
抗原
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