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SOX3 抗体 (AA 256-283)

This anti-SOX3 antibody is a 兔 多克隆 antibody detecting SOX3 in WB, ELISA 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7600935
发货至: 中国

Quick Overview for SOX3 抗体 (AA 256-283) (ABIN7600935)

抗原

See all SOX3 抗体
SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SOX3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 256-283

    原理

    Anti-SOX3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-SOX3 Antibody Picoband® (ABIN7600935). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SOX3 recombinant protein (Position: Q256-Q283).

    亚型

    IgG
  • 应用备注

    Western blot, 0.5-1 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. "Entrez Gene: SOX3 SRY (sex determining region Y)-box 3". 2. Woods KS, Cundall M, Turton J, Rizotti K, Mehta A, Palmer R, Wong J, Chong WK, Al-Zyoud M, El-Ali M, Otonkoski T, Martinez-Barbera JP, Thomas PQ, Robinson IC, Lovell-Badge R, Woodward KJ, Dattani MT (May 2005). "Over- and underdosage of SOX3 is associated with infundibular hypoplasia and hypopituitarism". American Journal of Human Genetics. 76 (5): 833-49.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    SOX3 (SRY (Sex Determining Region Y)-Box 3 (SOX3))

    别名

    SOX3

    背景

    Synonyms: Transcription factor SOX-3, SOX3

    Tissue Specificity: Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Isoform 2 is only detected in the apical membranes of polarized renal tubular cells and placenta. Isoform 1 and isoform 2 are detected in kidney membrane (at protein level).

    Background: Transcription factor SOX-3 is a protein that in humans is encoded by the SOX3 gene. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked cognitive disability with growth hormone deficiency.

    分子量

    45 kDa

    基因ID

    6658

    UniProt

    P41225
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