BRSK2 抗体 (AA 250-736)
Quick Overview for BRSK2 抗体 (AA 250-736) (ABIN7600926)
抗原
See all BRSK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-736
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原理
- Anti-BRSK2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-BRSK2 Antibody Picoband® (ABIN7600926). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human BRSK2 recombinant protein (Position: M250-P736).
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亚型
- IgG
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anti-BR serine/threonine Kinase 2 (BRSK2) (Internal Region) antibody
Verified BRSK2 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) antibodyBRSK2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) (AA 1-170) antibodyBRSK2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) (AA 706-736), (C-Term) antibodyBRSK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5548 unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) (C-Term) antibodyBRSK2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Kishi, M., Pan, Y. A., Crump, J. G., Sanes, Y. R. Mammalian SAD kinases are required for neuronal polarization. Science 307: 929-932, 2005. 2. Lu, R., Niida, H., Nakanishi, M. Human SAD1 kinase is involved in UV-induced DNA damage checkpoint function. J. Biol. Chem. 279: 31164-31170, 2004. 3. Miura, K., Masuzaki, H., Ishimaru, T., Niikawa, N., Jinno, Y. A HhaI/BstUI polymorphism in a novel gene at human chromosome 11p15.5. J. Hum. Genet. 43: 283-284, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- BRSK2 (BR serine/threonine Kinase 2 (BRSK2))
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别名
- BRSK2
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背景
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Synonyms: T-cell receptor alpha chain C region, TRAC, TCRA
Tissue Specificity: Expressed in testis and to a lesser degree in brain, ovary and placenta. Found in most tissues at low levels.
Background: BR serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the BRSK2 gene. BRSK2 was initially identified through a computer screen of the human genome and shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK2 is expressed in the brain and to a lesser extent in the testes. BRSK2 is a member of the AMP-activated protein kinase subfamily and can be activated by the tumor suppressor kinase LKB1. More recently, it has been shown that both BRSK2 and the related protein BRSK1 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. BRSK2 has also been shown to be an autoantigen in paraneoplastic limbic encephalitis. At least four isoforms of BRSK2 are known to exist.
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分子量
- 90 kDa
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基因ID
- 9024
抗原
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