Methionine--tRNA Ligase, Cytoplasmic (AA 25-887) 抗体
Quick Overview for Methionine--tRNA Ligase, Cytoplasmic (AA 25-887) 抗体 (ABIN7600923)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-887
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原理
- Anti-MARS1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-MARS1 Antibody Picoband® (ABIN7600923). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MARS1 recombinant protein (Position: R25-E887).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL/mL, Human
Flow Cytometry (Fixed), 1-3 μg/mL/1x10^6 cells, Human
ELISA, 0.1-0.5 μg/mL/mL, Human
1. Botta, E., Theil, A. F., Raams, A., Caligiuri, G., Giachetti, S., Bione, S., Accadia, M., Lombardi, A., Smith, D. E. C., Mendes, M. I., Swagemakers, S. M. A., van der Spek, P. J., Salomons, G. S., Hoeijmakers, J. H. J., Yesodharan, D., Nampoothiri, S., Ogi, T., Lehmann, A. R., Orioli, D., Vermeulen, W. Protein instability associated with AARS1 and MARS1 mutations causes trichothiodystrophy. Hum. Molec. Genet. 30: 1711-1720, 2021. 2. Cirullo, R. E., Wasmuth, J. J. Assignment of the human gene encoding methionyl-tRNA synthetase to chromosome 12. (Abstract) Cytogenet. Cell Genet. 37: 437 only, 1984. 3. Cirullo, R. E., Wasmuth, J. J. Assignment of the human MARS gene, encoding methioninyl-tRNA synthetase, to chromosome 12 using human x Chinese hamster cell hybrids. Somat. Cell Molec. Genet. 10: 225-234, 1984. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Methionine--tRNA Ligase, Cytoplasmic
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别名
- MARS1
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背景
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Synonyms: GTP-binding nuclear protein Ran,Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein,RAN,ARA24,OK/SW-cl.81,
Tissue Specificity: Expressed in a variety of tissues. .
Background: This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules.
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分子量
- 99 kDa
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基因ID
- 4141
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UniProt
- P56192
抗原
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