Secretin 抗体 (AA 25-65)
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- 抗原 See all Secretin (SECR) 抗体
- Secretin (SECR)
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抗原表位
- AA 25-65
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Secretin antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 原理
- Anti-Secretin/Sct Antibody
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-Secretin/Sct Antibody Picoband® (ABIN7600918). Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived mouse Secretin/Sct recombinant protein (Position: A25-D65).
- 亚型
- IgG
- Top Product
- Discover our top product SECR Primary Antibody
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anti-Secretin (SECR) (AA 26-133) antibody
SECR 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Secretin (SECR) antibodySECR 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Secretin (SECR) (AA 1-121) antibodySECR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Secretin (SECR) (N-Term) antibodySECR 适用: 人, 小鼠, 大鼠, Cow, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Bayliss, W., Starling, E. H. The mechanism of pancreatic secretion. J. Physiol. (London) 28: 325-353, 1902. 2. Chu, J. Y. S., Chung, S. C. K., Lam, A. K. M., Tam, S., Chung, S. K., Chow, B. K. C. Phenotypes developed in secretin receptor-null mice indicated a role for secretin in regulating renal water reabsorption. Molec. Cell Biol. 27: 2499-2511, 2007. 3. Chu, J. Y. S., Lee, L. T. O., Lai, C. H., Vaudry, H., Chan, Y. S., Yung, W. H., Chow, B. K. C. Secretin as a neurohypophysial factor regulating body water homeostasis. Proc. Nat. Acad. Sci. 106: 15961-15966, 2009. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- Secretin (SECR)
- 别名
- Sct (SECR 产品)
- 背景
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Synonyms: Pannexin-2, PANX2
Tissue Specificity: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.
Background: Secretin is a hormone that regulates water homeostasis throughout the body and influences the environment of the duodenum by regulating secretions in the stomach, pancreas, and liver. It is a peptide hormone produced in the S cells of the duodenum, which are located in the intestinal glands. In humans, the secretin peptide is encoded by the SCT gene. This gene encodes the precursor of a gastrointestinal peptide hormone of the secretin-glucagon family. The encoded protein is secreted as a prohormone that undergoes proteolytic processing to generate a mature peptide hormone. The mature peptide regulates secretion of gastric acid, biocarbonate ions from pancreatic and biliary duct epithelia and water homeostasis in the gastrointestinal system. Mice lacking the encoded protein display decreased survival of neuroprogenitor cells during early postnatal period and impaired long-term potentiation and spatial learning in adulthood. Alternative splicing results in multiple transcript variants encoding different isoforms. All of these isoforms may be processed in a similar manner to generate the mature peptide hormone.
- 分子量
- 70 kDa
- 基因ID
- 20287
- UniProt
- Q08535
- 途径
- Stem Cell Maintenance
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