Metabotropic Glutamate Receptor 1 抗体 (AA 25-466)
Quick Overview for Metabotropic Glutamate Receptor 1 抗体 (AA 25-466) (ABIN7600912)
抗原
See all Metabotropic Glutamate Receptor 1 (GRM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-466
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原理
- Anti-mGluR1/GRM1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-mGluR1/GRM1 Antibody Picoband® (ABIN7600912). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human mGluR1/GRM1 recombinant protein (Position: R25-E466).
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亚型
- IgG
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anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 165-592) antibody
GRM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 501-516), (Extracellular) antibodyGRM1 适用: 大鼠 WB, IP, IF, IC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) antibodyGRM1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 387-486) antibodyGRM1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5E12D8 unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 880-1017) antibodyGRM1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (C-Term) antibodyGRM1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (N-Term) antibodyGRM1 适用: 人, Cow, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 387-486) antibodyGRM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F7 unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (Internal Region) antibodyGRM1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 1 (GRM1) (AA 387-486) antibodyGRM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Ganesh, S., Amano, K., Yamakawa, K. Assignment of the gene GRM1 coding for metabotropic glutamate receptor 1 to human chromosome band 6q24 by in situ hybridization. Cytogenet. Cell Genet. 88: 314-315, 2000. 2. Ortiz, P., Vanaclocha, F., Lopez-Bran, E., Esquivias, J. I., Lopez-Estebaranz, J. L., Martin-Gonzalez, M., Arrue, I., Garcia-Romero, D., Ochoa, C., Gonzalez-Perez, A., Ruiz, A., Real, L. M. Genetic analysis of the GRM1 gene in human melanoma susceptibility. Europ. J. Hum. Genet. 15: 1176-1182, 2007. 3. Sachs, A. J., Schwendinger, J. K., Yang, A. W., Haider, N. B., Nystuen, A. M. The mouse mutants recoil wobbler and nmf373 represent a series of Grm1 mutations. Mammalian Genome 18: 749-756, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
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别名
- GRM1
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背景
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Synonyms: Calbindin, Calbindin D28, D-28K, Vitamin D-dependent calcium-binding protein, avian-type, CALB1, CAB27
Tissue Specificity: Detected in skin. In the cornea, it is detected in the epithelial basement membrane, the epithelial cells, and at a lower level in stromal cells. Stratified squamous epithelia. Found in hemidesmosomes. Expressed in cornea, oral mucosa, esophagus, intestine, kidney collecting ducts, ureter, bladder, urethra and thymus but is absent in lung, blood vessels, skeletal muscle and nerves.
Background: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 132 kDa
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基因ID
- 2911
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UniProt
- Q13255
抗原
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