SUCLG1 抗体 (AA 25-346)
Quick Overview for SUCLG1 抗体 (AA 25-346) (ABIN7600906)
抗原
See all SUCLG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-346
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原理
- Anti-SUCLG1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SUCLG1 Antibody Picoband® (ABIN7600906). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SUCLG1 recombinant protein (Position: R25-K346).
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亚型
- IgG
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anti-Succinate-CoA Ligase, alpha Subunit (SUCLG1) antibody
KO Validated SUCLG1 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Succinate-CoA Ligase, alpha Subunit (SUCLG1) (AA 41-346) antibodySUCLG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Succinate-CoA Ligase, alpha Subunit (SUCLG1) (AA 125-234) antibodySUCLG1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Succinate-CoA Ligase, alpha Subunit (SUCLG1) (AA 210-316) antibodySUCLG1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chinopoulos, C., Batzios, S., van den Heuvel, L. P., Rodenburg, R., Smeets, R., Waterham, H. R., Turkenburg, M., Ruiter, J. P., Wanders, R. J. A., Doczi, J., Horvath, G., Dobolyi, A., Vargiami, E., Wevers, R. A., Zafeiriou, D. Mutated SUCLG1 causes mislocalization of SUCLG2 protein, morphological alterations of mitochondria and an early-onset severe neurometabolic disorder. Molec. Genet. Metab. 126: 43-52, 2019. 2. Gross, M. B. Personal Communication. Baltimore, Md. 5/29/2015. 3. James, M., Man, N., Edwards, Y. H., Morris, G. E. The molecular basis for cross-reaction of an anti-dystrophin antibody with alpha-actinin. Biochim. Biophys. Acta 1360: 169-176, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SUCLG1 (Succinate-CoA Ligase, alpha Subunit (SUCLG1))
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别名
- SUCLG1
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背景
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Synonyms: ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, HuB, Nervous system-specific RNA-binding protein Hel-N1, ELAVL2, HUB
Tissue Specificity: Brain, neural-specific.
Background: Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial is an enzyme that in humans is encoded by the SUCLG1 gene. This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion.
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分子量
- 35 kDa
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基因ID
- 8802
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UniProt
- P53597
抗原
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