CA4 抗体 (AA 25-291)
Quick Overview for CA4 抗体 (AA 25-291) (ABIN7600898)
抗原
See all CA4 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 25-291
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                                            原理
- Anti-Carbonic Anhydrase 4/CA4 Picoband® Antibody
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                                            交叉反应 (详细)
- No cross-reactivity with other proteins.
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                                            产品特性
- Anti-Carbonic Anhydrase 4/CA4 Picoband® Antibody (ABIN7600898). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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                                            纯化方法
- Immunogen affinity purified.
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                                            免疫原
- E.coli-derived mouse Carbonic Anhydrase 4/CA4 recombinant protein (Position: E25-L291).
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                                            亚型
- IgG
 
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                                            应用备注
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                        Western blot, 0.25-0.5 μg/mL, Mouse, Rat
 Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
 Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
 ELISA, 0.1-0.5 μg/mL, -
 1. Alvarez, B. V., Vithana, E. N., Yang, Z., Koh, A. H., Yeung, K., Yong, V., Shandro, H. J., Chen, Y., Kolatkar, P., Palasingam, P., Zhang, K., Aung, T., Casey, J. R. Identification and characterization of a novel mutation in the carbonic anhydrase IV gene that causes retinitis pigmentosa. Invest. Ophthal. Vis. Sci. 48: 3459-3468, 2007. 2. Bardien, S., Ebenezer, N., Greenberg, J., Inglehearn, C. F., Bartmann, L., Goliath, R., Beighton, P., Ramesar, R., Bhattacharya, S. S. An eighth locus for autosomal dominant retinitis pigmentosa is linked to chromosome 17q. Hum. Molec. Genet. 4: 1459-1462, 1995. 3. Bardien, S., Ramesar, R., Bhattacharya, S., Greenberg, J. Retinitis pigmentosa locus on 17q (RP17): fine localization to 17q22 and exclusion of the PDEG and TIMP2 genes. Hum. Genet. 101: 13-17, 1997.
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                                            限制
- 仅限研究用
 
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                                            状态
- Lyophilized
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                                            溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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                                            浓度
- 500 μg/mL
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                                            缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
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                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
 
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    - CA4 (Carbonic Anhydrase IV (CA4))
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                                            别名
- Ca4
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                                            背景
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                        Synonyms: Carbonic anhydrase 4, Carbonate dehydratase IV, Carbonic anhydrase IV, CA-IV, Ca4, Car4 Tissue Specificity: Expressed in the endothelium of the choriocapillaris in eyes (at protein level). Not expressed in the retinal epithelium at detectable levels. . Background: Carbonic anhydrase 4 is an enzyme that in humans is encoded by the CA4 gene. It is mapped to 11, 11 C. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport. 
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                                            分子量
- 35 kDa
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                                            基因ID
- 12351
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                                            UniProt
- Q64444
 抗原
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