NRF1 抗体 (AA 246-503)
Quick Overview for NRF1 抗体 (AA 246-503) (ABIN7600874)
抗原
See all NRF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 246-503
-
原理
- Anti-NRF1 Antibody Picoband® (monoclonal, 2G4)
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-NRF1 Antibody Picoband® (monoclonal, 2G4) (ABIN7600874). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human NRF1 recombinant protein (Position: D246-Q503).
-
亚型
- IgG2a
-
-
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 201-285) antibody
NRF1 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) antibodyNRF1 适用: 人 WB, IHC (p), IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 272-288), (Middle Region) antibodyNRF1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (Middle Region) antibodyNRF1 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 豚鼠, 斑马鱼, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) antibodyNRF1 适用: 人 WB, IHC, IP, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (N-Term) antibodyNRF1 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 豚鼠, 斑马鱼, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 51-180) antibodyNRF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 360-409) antibodyNRF1 适用: 人, 大鼠, Cow, 兔, 马, 豚鼠, 斑马鱼, 犬, 猴, 小鸡, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (Internal Region) antibodyNRF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Respiratory Factor 1 (NRF1) (AA 1-300) antibodyNRF1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Efiok, B. J. S., Chiorini, J. A., Safer, B. A key transcription factor for eukaryotic initiation factor-2-alpha is strongly homologous to developmental transcription factors and may link metabolic genes to cellular growth and development. J. Biol. Chem. 269: 18921-18930, 1994. 2. Gopalakrishnan, L., Scarpulla, R. C. Structure, expression, and chromosomal assignment of the human gene encoding nuclear respiratory factor 1. J. Biol. Chem. 270: 18019-18025, 1995. 3. Virbasius, J. V., Scarpulla, R. C. Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis. Proc. Nat. Acad. Sci. 91: 1309-1313, 1994. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
-
别名
- NRF1
-
背景
-
Synonyms: Nuclear respiratory factor 1, NRF-1, Alpha palindromic-binding protein, Alpha-pal, NRF1
Tissue Specificity: Ubiquitously expressed with strongest expression in skeletal muscle.
Background: Nuclear respiratory factor 1, is also known as NRF1. This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1.
-
分子量
- 54-70 kDa
-
基因ID
- 4899
-
UniProt
- Q16656
-
途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
-
