CCL7 抗体 (AA 24-97)
Quick Overview for CCL7 抗体 (AA 24-97) (ABIN7600861)
抗原
See all CCL7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 24-97
-
原理
- Anti-Ccl7 Antibody Picoband®
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
产品特性
- Anti-Ccl7 Antibody Picoband® (ABIN7600861). Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived rat Ccl7 recombinant protein (Position: Q24-P97).
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Rat
ELISA, 0.1-0.5 μg/mL, Rat
1. Ong, V. H., Evans, L. A., Shiwen, X., Fisher, I. B., Rajkumar, V., Abraham, D. J., Black, C. M., Denton, C. P.Monocyte chemoattractant protein 3 as a mediator of fibrosis: overexpression in systemic sclerosis and the type 1 tight-skin mouse.Arthritis Rheum. 48: 1979-1991, 2003. 2. McQuibban, G. A., Gong, J.-H., Tam, E. M., McCulloch, C. A. G., Clark-Lewis, I., Overall, C. M.Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3.Science 289: 1202-1206, 2000. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
-
别名
- Ccl7
-
背景
-
Synonyms: Fatty acid-binding protein, intestinal,Fatty acid-binding protein 2,Intestinal-type fatty acid-binding protein,I-FABP,Fabp2,Fabpi,
Tissue Specificity: Expressed in the small intestine. Highest expression levels in the proximal ileum. .
Background: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, MCP3 gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response.
-
分子量
- 9 kDa
-
基因ID
- 287561
抗原
-