DCT 抗体 (AA 24-519)
Quick Overview for DCT 抗体 (AA 24-519) (ABIN7600843)
抗原
See all DCT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-519
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原理
- Anti-TRP2/DCT Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TRP2/DCT Antibody Picoband® (ABIN7600843). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TRP2/DCT recombinant protein (Position: Q24-A519).
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亚型
- IgG
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anti-Dopachrome Tautomerase (DCT) (N-Term) antibody
DCT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dopachrome Tautomerase (DCT) (AA 1268-1341) antibodyDCT 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dopachrome Tautomerase (DCT) (AA 28-263) antibodyDCT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dopachrome Tautomerase (DCT) (AA 62-89), (N-Term) antibodyDCT 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB23480 unconjugated
anti-Dopachrome Tautomerase (DCT) (Center) antibodyDCT 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Dopachrome Tautomerase (DCT) (Middle Region) antibodyDCT 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 兔, 绵羊, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dopachrome Tautomerase (DCT) (AA 62-89), (N-Term) antibodyDCT 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Dopachrome Tautomerase (DCT) (Internal Region) antibodyDCT 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Dopachrome Tautomerase (DCT) (AA 1268-1341) antibodyDCT 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dopachrome Tautomerase (DCT) (AA 44-205) antibodyDCT 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bouchard, B., Del Marmol, V., Jackson, I. J., Cherif, D., Dubertret, L. Molecular characterization of a human tyrosinase-related-protein-2 cDNA: patterns of expression in melanocytic cells. Europ. J. Biochem. 219: 127-134, 1994. 2. Budd, P. S., Jackson, I. J. Structure of the mouse tyrosinase-related protein-2/dopachrome tautomerase (Tyrp2/Dct) gene and sequence of two novel slaty alleles. Genomics 29: 35-43, 1995. 3. Cassady, J. L., Sturm, R. A. Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA. Gene 143: 295-298, 1994. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- DCT (Dopachrome Tautomerase (DCT))
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别名
- DCT
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背景
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Synonyms: Beta-galactosidase, Glb1, Glb1_mapped, rCG_25043
Background: Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.
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分子量
- 59 kDa
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基因ID
- 1638
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UniProt
- P40126
抗原
-
