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NAGLU 抗体 (AA 24-489)

NAGLU 适用: 小鼠, 大鼠, 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7600838
发货至: 中国
  • 抗原 See all NAGLU 抗体
    NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))
    抗原表位
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 24-489
    适用
    • 10
    • 7
    • 5
    • 1
    • 1
    • 1
    小鼠, 大鼠, 人
    宿主
    • 17
    • 4
    克隆类型
    • 18
    • 3
    多克隆
    标记
    • 13
    • 4
    • 4
    This NAGLU antibody is un-conjugated
    应用范围
    • 20
    • 9
    • 7
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA
    原理
    Anti-NAGLU Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-NAGLU Antibody Picoband® (ABIN7600838). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human NAGLU recombinant protein (Position: D24-D489).
    亚型
    IgG
    Top Product
    Discover our top product NAGLU Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL
    1. Beesley, C. E., Young, E. P., Vellodi, A., Winchester, B. G. Identification of 12 novel mutations in the alpha-N-acetylglucosaminidase gene in 14 patients with Sanfilippo syndrome type B (mucopolysaccharidosis type IIIB). J. Med. Genet. 35: 910-914, 1998. 2. Bunge, S., Knigge, A., Steglich, C., Kleijer, W. J., van Diggelen, O. P., Beck, M., Gal, A. Mucopolysaccharidosis type IIIB (Sanfilippo B): identification of 18 novel alpha-N-acetylglucosaminidase gene mutations. J. Med. Genet. 36: 28-31, 1999. 3. Chinen, Y., Tohma, T., Izumikawa, Y., Uehara, H., Ohta, T. Sanfilippo type B syndrome: five patients with an R565P homozygous mutation in the alpha-N-acetylglucosaminidase gene from the Okinawa islands in Japan. J. Hum. Genet. 50: 357-359, 2005.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))
    别名
    NAGLU (NAGLU 产品)
    背景

    Synonyms: NAGLU, UFHSD1, Alpha-N-acetylglucosaminidase, EC 3.2.1.50, N-acetyl-alpha-glucosaminidase, NAG [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form, Alpha-N-acetylglucosaminidase 77 kDa form]

    Background: N-acetylglucosaminidase, alpha is a protein that in humans is encoded by the NAGLU gene. This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.

    分子量
    82 kDa
    基因ID
    4669
    UniProt
    P54802
    途径
    Glycosaminoglycan Metabolic Process
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