NAGLU 抗体 (AA 24-489)
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- 抗原 See all NAGLU 抗体
- NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))
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抗原表位
- AA 24-489
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适用
- 小鼠, 大鼠, 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NAGLU antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Anti-NAGLU Antibody Picoband®
- 交叉反应 (详细)
- No cross-reactivity with other proteins
- 产品特性
- Anti-NAGLU Antibody Picoband® (ABIN7600838). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human NAGLU recombinant protein (Position: D24-D489).
- 亚型
- IgG
- Top Product
- Discover our top product NAGLU Primary Antibody
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL
1. Beesley, C. E., Young, E. P., Vellodi, A., Winchester, B. G. Identification of 12 novel mutations in the alpha-N-acetylglucosaminidase gene in 14 patients with Sanfilippo syndrome type B (mucopolysaccharidosis type IIIB). J. Med. Genet. 35: 910-914, 1998. 2. Bunge, S., Knigge, A., Steglich, C., Kleijer, W. J., van Diggelen, O. P., Beck, M., Gal, A. Mucopolysaccharidosis type IIIB (Sanfilippo B): identification of 18 novel alpha-N-acetylglucosaminidase gene mutations. J. Med. Genet. 36: 28-31, 1999. 3. Chinen, Y., Tohma, T., Izumikawa, Y., Uehara, H., Ohta, T. Sanfilippo type B syndrome: five patients with an R565P homozygous mutation in the alpha-N-acetylglucosaminidase gene from the Okinawa islands in Japan. J. Hum. Genet. 50: 357-359, 2005. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))
- 别名
- NAGLU (NAGLU 产品)
- 背景
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Synonyms: NAGLU, UFHSD1, Alpha-N-acetylglucosaminidase, EC 3.2.1.50, N-acetyl-alpha-glucosaminidase, NAG [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form, Alpha-N-acetylglucosaminidase 77 kDa form]
Background: N-acetylglucosaminidase, alpha is a protein that in humans is encoded by the NAGLU gene. This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.
- 分子量
- 82 kDa
- 基因ID
- 4669
- UniProt
- P54802
- 途径
- Glycosaminoglycan Metabolic Process
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