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CDC25C 抗体 (AA 24-447)

This anti-CDC25C antibody is a 兔 多克隆 antibody detecting CDC25C in WB 和 ELISA. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7600835
发货至: 中国

Quick Overview for CDC25C 抗体 (AA 24-447) (ABIN7600835)

抗原

See all CDC25C 抗体
CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

适用

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  • 45
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  • 1
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  • 1
  • 1
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  • 1
小鼠, 大鼠

宿主

  • 101
  • 16

克隆类型

  • 97
  • 20
多克隆

标记

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  • 6
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  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
This CDC25C antibody is un-conjugated

应用范围

  • 93
  • 49
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  • 26
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  • 16
  • 14
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  • 3
  • 2
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Western Blotting (WB), ELISA
  • 抗原表位

    • 25
    • 19
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-447

    原理

    Anti-Cdc25c Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Cdc25c Antibody Picoband® (ABIN7600835). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Cdc25c recombinant protein (Position: K24-Q447).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. "Entrez Gene: CDC25C cell division cycle 25 homolog C (S. pombe)". 2. Gould KL, Moreno S, Tonks NK, Nurse P (Feb 1991). "Complementation of the mitotic activator, p80cdc25, by a human protein-tyrosine phosphatase". Science 250 (4987): 1573-6. 3. Sartor H, Ehlert F, Grzeschik KH, et al. (1992). "Assignment of two human cell cycle genes, CDC25C and CCNB1, to 5q31 and 5q12, respectively". Genomics 13(3): 911-2.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

    别名

    Cdc25c

    背景

    Synonyms: Metabotropic glutamate receptor 5, mGluR5, GRM5, GPRC1E, MGLUR5

    Tissue Specificity: Isoform 1 and isoform 2 are detected in bone marrow cells, spermatogonia and spermatocytes, but not in round spermatids, elongating spermatids and spermatozoa. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa, but not in spermatogonia and spermatocytes (at protein level). Isoform 1 is widely expressed and detected in fetal liver and bone marrow. Isoform 3 is detected in bone marrow cells enriched in hematopoietic stem cells.

    Background: M-phase inducer phosphatase 3is anenzymethat in humans is encoded by theCDC25Cgene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It s dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

    分子量

    53 kDa

    基因ID

    12532

    UniProt

    P48967

    途径

    Cell Division Cycle, M Phase
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