POU6F2 抗体 (AA 24-446)
Quick Overview for POU6F2 抗体 (AA 24-446) (ABIN7600834)
抗原
See all POU6F2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-446
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原理
- Anti-POU6F2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-POU6F2 Antibody Picoband® (ABIN7600834). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human POU6F2 recombinant protein (Position: E24-Q446). Human POU6F2 shares 89.7% amino acid (aa) sequence identity with mouse POU6F2.
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亚型
- IgG
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anti-POU Class 6 Homeobox 2 (POU6F2) (N-Term) antibody
Verified POU6F2 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-POU Class 6 Homeobox 2 (POU6F2) (AA 2-87) antibodyPOU6F2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D3 unconjugated
anti-POU Class 6 Homeobox 2 (POU6F2) (AA 604-653) antibodyPOU6F2 适用: 人, 小鼠, 犬, 豚鼠, 小鸡, 猴, 马, 斑马鱼, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-POU Class 6 Homeobox 2 (POU6F2) (N-Term) antibodyPOU6F2 适用: 人, 小鼠, 大鼠, Cow, 兔, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-POU Class 6 Homeobox 2 (POU6F2) (AA 35-84) antibodyPOU6F2 适用: 人, 大鼠, Cow, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL
1. Gross, M. B. Personal Communication. Baltimore, Md. 4/5/2019. 2. Perotti, D., De Vecchi, G., Testi, M. A., Lualdi, E., Modena, P., Mondini, P., Ravagnani, F., Collini, P., Di Renzo, F., Spreafico, F., Terenziani, M., Sozzi, G., Fossati-Bellani, F., Radice, P. Germline mutations of the POU6F2 gene in Wilms tumors with loss of heterozygosity on chromosome 7p14. Hum. Mutat. 24: 400-407, 2004. 3. Perotti, D., Testi, M. A., Mondini, P., Pilotti, S., Green, E. D., Pession, A., Sozzi, G., Pierotti, M. A., Fossati Bellani, F., Radice, P. Refinement within single yeast artificial chromosome clones of a minimal region commonly deleted on the short arm of chromosome 7 in Wilms tumours. Genes Chromosomes Cancer 31: 42-47, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- POU6F2 (POU Class 6 Homeobox 2 (POU6F2))
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别名
- POU6F2
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背景
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Synonyms: POU6F2, RPF1, POU domain, class 6, transcription factor 2, Retina-derived POU domain factor 1, RPF-1
Background: This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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分子量
- 73 kDa
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基因ID
- 11281
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UniProt
- P78424
抗原
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