DLK1 抗体 (AA 24-383)
Quick Overview for DLK1 抗体 (AA 24-383) (ABIN7600828)
抗原
See all DLK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-383
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原理
- Anti-DLK-1/DLK1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-DLK-1/DLK1 Antibody Picoband® (ABIN7600828). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DLK-1/DLK1 recombinant protein (Position: A24-I383).
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亚型
- IgG
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anti-delta-Like 1 Homolog (Drosophila) (DLK1) antibody
DLK1 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A10 unconjugated
anti-delta-Like 1 Homolog (Drosophila) (DLK1) (AA 251-350) antibodyDLK1 适用: 人, 小鼠, 大鼠, 绵羊 WB, ELISA, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-delta-Like 1 Homolog (Drosophila) (DLK1) (AA 368-402), (C-Term) antibodyDLK1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB51648 unconjugated
anti-delta-Like 1 Homolog (Drosophila) (DLK1) (Extracellular Domain) antibodyDLK1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal PF299-1 unconjugated
anti-delta-Like 1 Homolog (Drosophila) (DLK1) (AA 83-383) antibodyDLK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-delta-Like 1 Homolog (Drosophila) (DLK1) (C-Term) antibodyDLK1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-303) antibodyDLK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-delta-Like 1 Homolog (Drosophila) (DLK1) (AA 1-383) antibodyDLK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-delta-Like 1 Homolog (Drosophila) (DLK1) (AA 177-326) antibodyDLK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-delta-Like 1 Homolog (Drosophila) (DLK1) (Extracellular Domain) antibodyDLK1 适用: 小鼠 WB, ELISA 宿主: 大鼠 Monoclonal PF105B unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cleaton, M. A. M., Dent, C. L., Howard, M., Corish, J. A., Gutteridge, I., Sovio, U., Gaccioli, F., Takahashi, N., Bauer, S. R., Charnock-Jones, D. S., Powell, T. L., Smith, G. C. S., Ferguson-Smith, A. C., Charalambous, M. Fetus-derived DLK1 is required for maternal metabolic adaptations to pregnancy and is associated with fetal growth restriction. Nature Genet. 48: 1473-1480, 2016. 2. Cockett, N. E., Jackson, S. P., Shay, T. L., Farnir, F., Berghmans, S., Snowder, G. D., Nielsen, D. M., Georges, M. Polar overdominance at the ovine callipyge locus. Science 273: 236-238, 1996. 3. Dauber, A., Cunha-Silva, M., Macedo, D. B., Brito, V. N., Abreu, A. P., Roberts, S. A., Montenegro, L. R., Andrew, M., Kirby, A., Weirauch, M. T., Labilloy, G., Bessa, D. S., Carroll, R. S., Jacobs, D. C., Chappell, P. E., Mendonca, B. B., Haig, D., Kaiser, U. B., Latronico, A. C. Paternally inherited DLK1 deletion associated with familial central precocious puberty. J. Clin. Endocr. Metab. 102: 1557-1567, 2017. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
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别名
- DLK1
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背景
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Synonyms: Cyclin-dependent-like kinase 5, Cell division protein kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit, TPKII catalytic subunit, CDK5, CDKN5
Tissue Specificity: Isoform 1 is ubiquitously expressed. Accumulates in cortical neurons (at protein level). Isoform 2 has only been detected in testis, skeletal muscle, colon, bone marrow and ovary.
Background: Protein delta homolog 1 is a protein that in humans is encoded by the DLK1 gene. This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.
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分子量
- 50 kDa
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基因ID
- 8788
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UniProt
- P80370
抗原
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