TSPYL5 抗体 (AA 24-337)
Quick Overview for TSPYL5 抗体 (AA 24-337) (ABIN7600825)
抗原
See all TSPYL5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-337
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原理
- Anti-TSPYL5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TSPYL5 Antibody Picoband® (ABIN7600825). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TSPYL5 recombinant protein (Position: R24-Q337).
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亚型
- IgG
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anti-TSPY-Like 5 (TSPYL5) (AA 251-350) antibody
TSPYL5 适用: 小鼠 FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TSPY-Like 5 (TSPYL5) (AA 344-372) antibodyTSPYL5 适用: 小鼠, 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TSPY-Like 5 (TSPYL5) (AA 344-372), (C-Term) antibodyTSPYL5 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32765 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Epping, M. T., Meijer, L. A. T., Krijgsman, O., Bos, J. L., Pandolfi, P. P., Bernards, R. TSPYL5 suppresses p53 levels and function by physical interaction with USP7. Nature Cell Biol. 13: 102-108, 2011. 2. Jung, Y., Park, J., Bang, Y.-J., Kim, T.-Y. Gene silencing of TSPYL5 mediated by aberrant promoter methylation in gastric cancers. Lab. Invest. 88: 153-160, 2008. 3. Kim, E. J., Lee, S. Y., Kim, T. R., Choi, S. I., Cho, E. W., Kim, K. C., Kim, I. G. TSPYL5 is involved in cell growth and the resistance to radiation in A549 cells via the regulation of p21(WAF1/Cip1) and PTEN/AKT pathway. Biochem. Biophys. Res. Commun. 392: 448-453, 2010. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TSPYL5 (TSPY-Like 5 (TSPYL5))
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别名
- TSPYL5
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背景
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Synonyms: RNA-binding protein Nova-2, Astrocytic NOVA1-like RNA-binding protein, Neuro-oncological ventral antigen 2, NOVA2, ANOVA, NOVA3
Tissue Specificity: Brain. Expression restricted to astrocytes.
Background: TSPY like 5 is a protein that in humans is encoded by the TSPYL5 gene. Predicted to enable chromatin binding activity and histone binding activity. Involved in several processes, including cellular response to gamma radiation, positive regulation of protein kinase B signaling, and positive regulation of protein ubiquitination. Predicted to be active in chromatin and nucleus.
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分子量
- 48 kDa
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基因ID
- 85453
抗原
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