QPRT 抗体 (AA 24-297)
Quick Overview for QPRT 抗体 (AA 24-297) (ABIN7600821)
抗原
See all QPRT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-297
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原理
- Anti-QPRT Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-QPRT Antibody Picoband® (ABIN7600821). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human QPRT recombinant protein (Position: R24-H297).
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亚型
- IgG
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anti-Quinolinate Phosphoribosyltransferase (QPRT) (AA 198-297) antibody
QPRT 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5D11 unconjugated
anti-Quinolinate Phosphoribosyltransferase (QPRT) (AA 198-297) antibodyQPRT 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) antibodyQPRT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Quinolinate Phosphoribosyltransferase (QPRT) (AA 113-254) antibodyQPRT 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) antibodyQPRT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Quinolinate Phosphoribosyltransferase (QPRT) (AA 206-234), (C-Term) antibodyQPRT 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fukuoka, S.-I., Nyaruhucha, C. M., Shibata, K. Characterization and functional expression of the cDNA encoding human brain quinolinate phosphoribosyltransferase. Biochim. Biophys. Acta 1395: 192-201, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
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别名
- QPRT
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背景
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Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6
Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.
Background: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.
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分子量
- 31-35 kDa
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基因ID
- 23475
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UniProt
- Q15274
抗原
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