LHX4 抗体 (AA 238-390)
Quick Overview for LHX4 抗体 (AA 238-390) (ABIN7600792)
抗原
See all LHX4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 238-390
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原理
- Anti-LHX4 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-LHX4 Antibody Picoband® (ABIN7600792). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LHX4 recombinant protein (Position: S238-F390).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Castinetti, F., Saveanu, A., Reynaud, R., Quentien, M. H., Buffin, A., Brauner, R., Kaffel, N., Albarel, F., Guedj, A. M., El Kholy, M., Amin, M., Enjalbert, A., Barlier, A., Brue, T. A novel dysfunctional LHX4 mutation with high phenotypical variability in patients with hypopituitarism. J. Clin. Endocr. Metab. 93: 2790-2799, 2008. 2. Dawid, I. B., Toyama, R., Taira, M. LIM domain proteins. C. R. Acad. Sci. III 318: 295-306, 1995. 3. Kawamata, N., Sakajiri, S., Sugimoto, K., Isobe, Y., Kobayashi, H., Oshimi, K. A novel chromosomal translocation t(1,14)(q25,q32) in pre-B acute lymphoblastic leukemia involves the LIM homeodomain protein gene, Lhx4. Oncogene 21: 4983-4991, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- LHX4 (LIM Homeobox 4 (LHX4))
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别名
- LHX4
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背景
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Synonyms: Atypical chemokine receptor 2, C-C chemokine receptor D6, Chemokine receptor CCR-10, Chemokine receptor CCR-9, Chemokine-binding protein 2, Chemokine-binding protein D6, ACKR2, CCBP2, CCR10, CMKBR9, D6
Tissue Specificity: Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors. Expressed at high levels in Kaposi sarcoma-related pathologies. Expressed on apoptotic neutrophils (at protein level). Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node.
Background: LIM/homeobox protein Lhx4 is a protein that in humans is encoded by the LHX4 gene. This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor involved in the control of differentiation and development of the pituitary gland. Mutations in this gene cause combined pituitary hormone deficiency 4.
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分子量
- 43 kDa
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基因ID
- 89884
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UniProt
- Q969G2
抗原
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