NAB2 抗体 (AA 235-525)
Quick Overview for NAB2 抗体 (AA 235-525) (ABIN7600786)
抗原
See all NAB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 235-525
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原理
- Anti-NAB2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-NAB2 Antibody Picoband® (ABIN7600786). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NAB2 recombinant protein (Position: D235-Q525). Human NAB2 shares 96.6% amino acid (aa) sequence identity with mouse NAB2.
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亚型
- IgG
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anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) antibody
NAB2 适用: 人 WB, IHC (p), IP, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) (AA 1-200) antibodyNAB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) (C-Term) antibodyNAB2 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) (AA 1-241) antibodyNAB2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) (AA 421-525) antibodyNAB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) (AA 221-320) antibodyNAB2 适用: 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) (AA 401-450) antibodyNAB2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 豚鼠, Pig, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) (AA 1-241) antibodyNAB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) (N-Term) antibodyNAB2 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2) (C-Term) antibodyNAB2 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, 豚鼠, Pig, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Chmielecki, J., Crago, A. M., Rosenberg, M., O'Connor, R., Walker, S. R., Ambrogio, L., Auclair, D., McKenna, A., Heinrich, M. C., Frank, D. A., Meyerson, M. Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors. Nature Genet. 45: 131-135, 2013. 2. Le, N., Nagarajan, R., Wang, J. Y. T., Svaren, J., LaPash, C., Araki, T., Schmidt, R. E., Milbrandt, J. Nab proteins are essential for peripheral nervous system myelination. Nature Neurosci. 8: 932-940, 2005. 3. Robinson, D. R., Wu, Y.-M., Kalyana-Sundaram, S., Cao, X., Lonigro, R. J., Sung, Y.-S., Chen, C.-L., Zhang, L., Wang, R., Su, F., Iyer, M. K., Roychowdhury, S., and 9 others. Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing. Nature Genet. 45: 180-185, 2013. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))
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别名
- NAB2
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背景
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Synonyms: NAB2, MADER, NGFI-A-binding protein 2, EGR-1-binding protein 2, Melanoma-associated delayed early response protein, Protein MADER
Background: NGFI-A-binding protein 2 also known as EGR-1-binding protein 2 or melanoma-associated delayed early response protein (MADER) is a protein that in humans is encoded by the NAB2 gene. This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
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分子量
- 57 kDa
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基因ID
- 4665
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UniProt
- Q15742
抗原
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