RED1 抗体 (AA 234-714)
Quick Overview for RED1 抗体 (AA 234-714) (ABIN7600784)
抗原
See all RED1 (ADARB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 234-714
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原理
- Anti-RED1/ADARB1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RED1/ADARB1 Antibody Picoband® (ABIN7600784). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RED1/ADARB1 recombinant protein (Position: K234-R714).
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亚型
- IgG
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anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) (AA 1-741) antibody
ADARB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) (Internal Region) antibodyADARB1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) (N-Term) antibodyADARB1 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 犬, 马, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) (Center) antibodyADARB1 适用: 人, 大鼠, 小鼠, 斑马鱼, 小鸡 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) (Internal Region) antibodyADARB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) antibodyADARB1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) (Internal Region) antibodyADARB1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) (AA 40-89) antibodyADARB1 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, Hamster, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) (N-Term) antibodyADARB1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Deaminase, RNA-Specific, B1 (ADARB1) antibodyADARB1 适用: 大鼠 WB, ICC 宿主: 绵羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Higuchi, M., Maas, S., Single, F. N., Hartner, J., Rozov, A., Burnashev, N., Feldmeyer, D., Sprengel, R., Seeburg, P. H. Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2. Nature 406: 78-81, 2000. 2. Lai, F., Chen, C.-X., Carter, K. C., Nishikura, K. Editing of glutamate receptor B subunit ion channel RNAs by four alternatively spliced DRADA2 double-stranded RNA adenosine deaminases. Molec. Cell. Biol. 17: 2413-2424, 1997. 3. Macbeth, M. R., Schubert, H. L., VanDemark, A. P., Lingam, A. T., Hill, C. P., Bass, B. L. Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing. Science 309: 1534-1539, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))
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别名
- ADARB1
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背景
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Synonyms: Glutamate receptor ionotropic, NMDA 1, GluN1, Glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1, NMD-R1, GRIN1, NMDAR1
Tissue Specificity: Widely expressed, with strongest expression in placenta (at protein level). Secreted by synovial fibroblasts. Up- regulated in osteoarthritis and rheumatoid arthritis synovial fluids and cartilage as compared with non-arthritic (at protein level).
Background: Double-stranded RNA-specific editase 1 is an enzyme that in humans is encoded by the ADARB1 gene. This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
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分子量
- 90 kDa
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基因ID
- 104
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UniProt
- P78563
抗原
-
