SIAE 抗体 (AA 230-523)
Quick Overview for SIAE 抗体 (AA 230-523) (ABIN7600774)
抗原
See all SIAE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-523
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原理
- Anti-SIAE Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SIAE Antibody Picoband® (ABIN7600774). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SIAE recombinant protein (Position: R230-K523).
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亚型
- IgG
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anti-Sialic Acid Acetylesterase (SIAE) (AA 1-523) antibody
SIAE 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sialic Acid Acetylesterase (SIAE) antibodySIAE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Acetylesterase (SIAE) (AA 270-450) antibodySIAE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Acetylesterase (SIAE) (AA 22-244) antibodySIAE 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cariappa, A., Takematsu, H., Liu, H., Diaz, S., Haider, K., Boboila, C., Kalloo, G., Connole, M., Shi, H. N., Varki, N., Varki, A., Pillai, S. B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esterase. J. Exp. Med. 206: 125-138, 2009. 2. Surolia, I., Pirnie, S. P., Chellappa, V., Taylor, K. N., Cariappa, A., Moya, J., Liu, H., Bell, D. W., Driscoll, D. R., Diederichs, S., Haider, K., Netravali, I., and 21 others. Functionally defective germline variants of sialic acid acetylesterase in autoimmunity. Nature 466: 243-247, 2010. 3. Takematsu, H., Diaz, S., Stoddart, A., Zhang, Y., Varki, A. Lysosomal and cytosolic sialic acid 9-O-acetylesterase activities can be encoded by one gene via differential usage of a signal peptide-encoding exon at the N terminus. J. Biol. Chem. 274: 25623-25631, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SIAE (Sialic Acid Acetylesterase (SIAE))
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别名
- SIAE
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背景
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Synonyms: BMP and activin membrane-bound inhibitor homolog, Non-metastatic gene A protein, Putative transmembrane protein, NMA, BAMBI, NMA
Tissue Specificity: Expressed in adult liver.
Background: This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.
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分子量
- 70 kDa
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基因ID
- 54414
抗原
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