PHC1 抗体 (AA 23-642)
Quick Overview for PHC1 抗体 (AA 23-642) (ABIN7600764)
抗原
See all PHC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-642
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原理
- Anti-PHC1 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-PHC1 Antibody Picoband® (ABIN7600764). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PHC1 recombinant protein (Position: R23-K642). Human PHC1 shares 93.6% amino acid (aa) sequence identity with mouse PHC1.
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亚型
- IgG
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anti-Polyhomeotic-Like 1 (PHC1) (AA 758-1004) antibody
PHC1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1F3F3 unconjugated
anti-Polyhomeotic-Like 1 (PHC1) (AA 1-957) antibodyPHC1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Polyhomeotic-Like 1 (PHC1) (AA 751-851) antibodyPHC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-Polyhomeotic-Like 1 (PHC1) (AA 758-1004) antibodyPHC1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Polyhomeotic-Like 1 (PHC1) (AA 1-957) antibodyPHC1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Polyhomeotic-Like 1 (PHC1) (AA 142-225) antibodyPHC1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polyhomeotic-Like 1 (PHC1) (AA 308-342) antibodyPHC1 适用: 人 WB 宿主: 兔 Polyclonal RB54227 unconjugated
anti-Polyhomeotic-Like 1 (PHC1) (AA 750-940) antibodyPHC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Alkema, M. J., Bronk, M., Verhoeven, E., Otte, A., van't Veer, L. J., Berns, A., van Lohuizen, M. Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex. Genes Dev. 11: 226-240, 1997. 2. Awad, S., Al-Dosari, M. S., Al-Yacoub, N., Colak, D., Salih, M. A., Alkuraya, F. S., Poizat, C. Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis. Hum. Molec. Genet. 22: 2200-2213, 2013. 3. Gunster, M. J., Satijn, D. P. E., Hamer, K. M., den Blaauwen, J. L., de Bruijn, D., Alkema, M. J., van Lohuizen, M., van Driel, R., Otte, A. P. Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic. Molec. Cell. Biol. 17: 2326-2335, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PHC1 (Polyhomeotic-Like 1 (PHC1))
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别名
- PHC1
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Polyhomeotic-like protein 1 is a protein that in humans is encoded by the PHC1 gene. This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein.
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分子量
- 140 kDa
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基因ID
- 1911
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UniProt
- P78364
抗原
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