SORBS1 抗体 (AA 23-323)
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- 抗原 See all SORBS1 抗体
- SORBS1 (Sorbin and SH3 Domain Containing 1 (SORBS1))
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抗原表位
- AA 23-323
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SORBS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 原理
- Anti-SORBS1 Picoband® Antibody
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-SORBS1 Picoband® Antibody (ABIN7600747). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human SORBS1 recombinant protein (Position: Q23-R323).
- 亚型
- IgG
- Top Product
- Discover our top product SORBS1 Primary Antibody
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anti-Sorbin and SH3 Domain Containing 1 (SORBS1) (AA 866-892) antibody
SORBS1 适用: 人, Hamster WB, IF 宿主: 兔 Polyclonal RB26778 unconjugated
anti-Sorbin and SH3 Domain Containing 1 (SORBS1) (C-Term) antibodyVerified SORBS1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Lin, W.-H., Chiu, K. C., Chang, H.-M., Lee, K.-C., Tai, T.-Y., Chuang, L.-M. Molecular scanning of the human sorbin and SH3-domain-containing-1 (SORBS1) gene: positive association of the T228A polymorphism with obesity and type 2 diabetes. Hum. Molec. Genet. 10: 1753-1760, 2001. 2. Mastick, C. C., Brady, M. J., Saltiel, A. R. Insulin stimulates the tyrosine phosphorylation of caveolin. J. Cell Biol. 129: 1523-1531, 1995. 3. Ribon, V., Printen, J. A., Hoffman, N. G., Kay, B. K., Saltiel, A. R. A novel, multifunctional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes. Molec. Cell. Biol. 18: 872-879, 1998. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- SORBS1 (Sorbin and SH3 Domain Containing 1 (SORBS1))
- 别名
- SORBS1 (SORBS1 产品)
- 背景
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Synonyms: Sorbin and SH3 domain-containing protein 1, Ponsin, SH3 domain protein 5, SH3P12, c-Cbl-associated protein, CAP, SORBS1, KIAA0894, KIAA1296, SH3D5
Tissue Specificity: Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.
Background: CAP/Ponsinprotein, also known as Sorbin and SH3 domain-containing protein 1 is a protein that in humans is encoded by the SORBS1 gene. It is mapped to 10q24.1. This gene encodes a CBL-associated protein which functions in the signaling and stimulation of insulin. Mutations in this gene may be associated with human disorders of insulin resistance. Alternative splicing results in multiple transcript variants.
- 分子量
- 160 kDa
- 基因ID
- 10580
- 途径
- Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process
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