GATA2 抗体 (AA 23-288)
Quick Overview for GATA2 抗体 (AA 23-288) (ABIN7600745)
抗原
See all GATA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-288
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原理
- Anti-GATA2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GATA2 Antibody Picoband® (ABIN7600745). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GATA2 recombinant protein (Position: D23-S288).
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亚型
- IgG
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anti-GATA Binding Protein 2 (GATA2) (AA 1-102) antibody
GATA2 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-GATA Binding Protein 2 (GATA2) (AA 1-102) antibodyGATA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F12 unconjugated
anti-GATA Binding Protein 2 (GATA2) (AA 1-102) antibodyGATA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-GATA Binding Protein 2 (GATA2) (N-Term) antibodyGATA2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 2 (GATA2) (AA 380-407) antibodyGATA2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 2 (GATA2) (AA 175-480) antibodyGATA2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 2 (GATA2) (AA 1-300) antibodyGATA2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 2 (GATA2) (AA 1-480) antibodyGATA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 2 (GATA2) antibodyGATA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 2 (GATA2) (AA 117-338) antibodyGATA2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ciciotte, S. L., Tsai, F.-Y., Peters, L. L.Gata2 maps to mouse chromosome 6.Mammalian Genome 8: 69-70, 1997. 2. Dorfman, D. M., Wilson, D. B., Bruns, G. A., Orkin, S. H.Human transcription factor GATA-2: evidence for regulation of preproendothelin-1 gene expression in endothelial cells.J. Biol. Chem. 267: 1279-1285, 1992. 3. Wieser, R., Volz, A., Vinatzer, U., Gardiner, K., Jager, U., Mitterbauer, M., Ziegler, A., Fonatsch, C.Transcription factor GATA-2 gene is located near 3q21 breakpoints in myeloid leukemia.Biochem. Biophys. Res. Commun. 273: 239-245, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GATA2 (GATA Binding Protein 2 (GATA2))
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别名
- GATA2
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背景
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Synonyms: Amiloride-sensitive sodium channel subunit alpha, Alpha-NaCH, Epithelial Na (+) channel subunit alpha, Alpha-ENaC, ENaCA, Nonvoltage-gated sodium channel 1 subunit alpha, SCNEA, SCNN1A, SCNN1
Tissue Specificity: Expressed in the female reproductive tract, from the fimbrial end of the fallopian tube to the endometrium (at protein level) (PubMed:22207244). Expressed in kidney (at protein level). In the respiratory tract, expressed in the bronchial epithelium (at protein level). Highly expressed in lung. Detected at intermediate levels in pancreas and liver, and at low levels in heart and placenta (PubMed:22207244). in skin, expressed in keratinocytes, melanocytes and Merkel cells of the epidermal sub- layers, stratum basale, stratum spinosum and stratum granulosum (at protein level) (PubMed:28130590). Expressed in the outer root sheath of the hair follicles (at protein level) (PubMed:28130590). Detected in both peripheral and central cells of the sebaceous gland (at protein level) (PubMed:28130590). Expressed by eccrine sweat glands (at protein level) (PubMed:28130590). In skin, also expressed by arrector pili muscle cells and intradermal adipocytes (PubMed:28130590). Isoform 1 and isoform 2 predominate in all tissues. Expression of isoform 3, isoform 4 and isoform 5 is very low or not detectable, except in lung and heart (PubMed:9575806).
Background: GATA2 (GATA binding protein 2) is a human gene which makes a protein called GATA binding protein 2 - a transcription factor. The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. Ciciotte et al. (1997)mapped the mouse Gata2 gene to chromosome 6 by study of DNA from an interspecific backcross panel. They pointed out that the human gene had been mapped to chromosome 3 by Dorfman et al. (1992) using DNA from a panel of 12 rodent/human hybrids containing various human chromosomes and applying Southern blot analysis. By exon trapping using a PAC contig spanning a breakpoint region associated with myeloid leukemia, Wieser et al. (2000) mapped the GATA2 gene to chromosome 3q21. GATA2 is transcribed from telomere to centromere. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.
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分子量
- 51 kDa
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基因ID
- 2624
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UniProt
- P23769
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途径
- Stem Cell Maintenance
抗原
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