CD3G 抗体 (AA 23-165)
Quick Overview for CD3G 抗体 (AA 23-165) (ABIN7600733)
抗原
See all CD3G 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-165
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原理
- Anti-CD3 Gamma/CD3G Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-CD3 Gamma/CD3G Antibody Picoband® (ABIN7600733). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CD3 Gamma/CD3G recombinant protein (Position: Q23-D165).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Arnaiz-Villena, A., Perez-Aciego, P., Ballestin, C., Sotelo, T., Perez-Seoane, C., Martin-Villa, J. M., Regueiro, J. R. Biochemical basis of a novel T lymphocyte receptor immunodeficiency by immunohistochemistry: a possible CD3-gamma abnormality. Lab. Invest. 64: 675-681, 1991. 2. Arnaiz-Villena, A., Timon, M., Corell, A., Perez-Aciego, P., Martin-Villa, J. M., Regueiro, J. R. Primary immunodeficiency caused by mutations in the gene encoding the CD3-gamma subunit of the T-lymphocyte receptor. New Eng. J. Med. 327: 529-533, 1992. 3. Das, S., Cotter, F. E., Gibbons, B., Dhut, S., Young, B. D. CD3G is within 200 kb of the leukemic t(4,11) translocation breakpoint. Genes Chromosomes Cancer 3: 44-47, 1991. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))
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别名
- CD3G
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背景
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Synonyms: Relaxin receptor 2, G-protein coupled receptor 106, G-protein coupled receptor affecting testicular descent, Leucine-rich repeat-containing G-protein coupled receptor 8, Relaxin family peptide receptor 2, RXFP2, GPR106, GREAT, LGR8
Tissue Specificity: Expressed mainly in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow.
Background: T-cell surface glycoprotein CD3 gamma chain is a protein that in humans is encoded by the CD3G gene. The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
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分子量
- 20-25 kDa
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基因ID
- 917
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UniProt
- P09693
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途径
- TCR Signaling, CXCR4-mediated Signaling Events
抗原
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