MYO1E 抗体 (AA 221-1065)
Quick Overview for MYO1E 抗体 (AA 221-1065) (ABIN7600705)
抗原
See all MYO1E 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 221-1065
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原理
- Anti-MYO1E Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MYO1E Antibody Picoband® (ABIN7600705). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MYO1E recombinant protein (Position: A221-Q1065). Human MYO1E shares 95.9% and 95.3% amino acid (aa) sequence identity with mouse and rat MYO1E, respectively.
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亚型
- IgG
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anti-Myosin IE (MYO1E) (AA 772-1033) antibody
MYO1E 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin IE (MYO1E) (AA 918-1014) antibodyMYO1E 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7A5 unconjugated
anti-Myosin IE (MYO1E) (AA 62-189) antibodyMYO1E 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myosin IE (MYO1E) (AA 781-1036) antibodyMYO1E 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin IE (MYO1E) (AA 228-257) antibodyMYO1E 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myosin IE (MYO1E) (C-Term) antibodyMYO1E 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Bement, W. M., Wirth, J. A., Mooseker, M. S. Cloning and mRNA expression of human unconventional myosin-IC: a homologue of amoeboid myosins-I with a single IQ motif and an SH3 domain. J. Molec. Biol. 243: 356-363, 1994. 2. Hasson, T., Skowron, J. F., Gilbert, D. J., Avraham, K. B., Perry, W. L., Bement, W. M., Anderson, B. L., Sherr, E. H., Chen, Z.-Y., Greene, L. A., Ward, D. C., Corey, D. P., Mooseker, M. S., Copeland, N. G., Jenkins, N. A. Mapping of unconventional myosins in mouse and human. Genomics 36: 431-439, 1996. 3. Krendel, M., Kim, S. V., Willinger, T., Wang, T., Kashgarian, M., Flavell, R. A., Mooseker, M. S. Disruption of myosin 1e promotes podocyte injury. J. Am. Soc. Nephrol. 20: 86-94, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MYO1E (Myosin IE (MYO1E))
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别名
- MYO1E
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背景
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Synonyms: MYO1E, MYO1C, Unconventional myosin-Ie, Myosin-Ic, Unconventional myosin 1E
Background: This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17.
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分子量
- 127 kDa
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基因ID
- 4643
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UniProt
- Q12965
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途径
- Platelet-derived growth Factor Receptor Signaling
抗原
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