PMVK 抗体 (AA 22-192)
Quick Overview for PMVK 抗体 (AA 22-192) (ABIN7600680)
抗原
See all PMVK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-192
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原理
- Anti-PMVK Antibody Picoband®
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产品特性
- Anti-PMVK Antibody Picoband® (ABIN7600680). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PMVK recombinant protein (Position: K22-L192). Human PMVK shares 82.5% amino acid (aa) sequence identity with mouse PMVK.
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anti-Phosphomevalonate Kinase (PMVK) (AA 1-192) antibody
PMVK 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2B8 unconjugated
anti-Phosphomevalonate Kinase (PMVK) (AA 1-192) antibodyPMVK 适用: 人 WB, ELISA, IF, ICC, FACS 宿主: 小鼠 Monoclonal AT21C10 unconjugated
anti-Phosphomevalonate Kinase (PMVK) (AA 1-192) antibodyPMVK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Phosphomevalonate Kinase (PMVK) (AA 1-192) antibodyPMVK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphomevalonate Kinase (PMVK) antibodyPMVK 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Phosphomevalonate Kinase (PMVK) antibodyPMVK 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1C12 unconjugated
anti-Phosphomevalonate Kinase (PMVK) (AA 15-120) antibodyPMVK 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphomevalonate Kinase (PMVK) (AA 1-192) antibodyPMVK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphomevalonate Kinase (PMVK) (AA 135-151), (Middle Region) antibodyPMVK 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphomevalonate Kinase (PMVK) (Middle Region) antibodyPMVK 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Chambliss, K. L., Slaughter, C. A., Schreiner, R., Hoffmann, G. F., Gibson, K. M. Molecular cloning of human phosphomevalonate kinase and identification of a consensus peroxisomal targeting sequence. J. Biol. Chem. 271: 17330-17334, 1996. 2. Olivier, L. M., Chambliss, K. L., Gibson, K. M., Krisans, S. K. Characterization of phosphomevalonate kinase: chromosomal localization, regulation, and subcellular targeting. J. Lipid Res. 40: 672-679, 1999. 3. Zhang, Z., Li, C., Wu, F., Ma, R., Luan, J., Yang, F., Liu, W., Wang, L., Zhang, S., Liu, Y., Gu, J., Hua, W., and 13 others. Genomic variations of the mevalonate pathway in porokeratosis. eLife 4: e06322, 2015. Note: Electronic Article. Erratum: eLife 5: e14383, 2016. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PMVK (Phosphomevalonate Kinase (PMVK))
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别名
- PMVK
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背景
- This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants.
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分子量
- 22 kDa
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基因ID
- 10654
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UniProt
- Q15126
抗原
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