电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TMEM52B 抗体 (AA 22-183)

This anti-TMEM52B antibody is a 兔 多克隆 antibody detecting TMEM52B in ELISA, WB 和 FACS. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7600679
发货至: 中国

Quick Overview for TMEM52B 抗体 (AA 22-183) (ABIN7600679)

抗原

TMEM52B (Transmembrane Protein 52B (TMEM52B))

适用

  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 猴

宿主

  • 6

克隆类型

  • 6
多克隆

标记

  • 2
  • 2
  • 1
  • 1
This TMEM52B antibody is un-conjugated

应用范围

ELISA, Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 5
    • 1
    AA 22-183

    原理

    Anti-TMEM52B Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-TMEM52B Antibody Picoband® (ABIN7600679). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TMEM52B recombinant protein (Position: T22-N183).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Zhang JX, et al. (2019) A positive feedback loop consisting of c12orf59/nf-κb/cdh11 promotes gastric cancer invasion and metastasis. J Exp Clin Cancer Res 38 (1): 164. 2. Xie J, et al. (2016) Down-regulation of c12orf59 is associated with a poor prognosis and vhl mutations in renal cell carcinoma. Oncotarget 7 (6): 6824-6834. 3. Clark HF, et al. (2003) The secreted protein discovery initiative (spdi), a large-scale effort to identify novel human secreted and transmembrane proteins: A bioinformatics assessment. Genome Res 13 (10): 2265-2270.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    TMEM52B (Transmembrane Protein 52B (TMEM52B))

    别名

    TMEM52B

    背景

    Synonyms: Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1, PYROXD1

    Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

    Background: TMEM52B (Transmembrane Protein 52B, also known as C12orf59) is a Protein Coding gene. The TMEM52B gene, located on 12p13.2, is conserved in chimpanzee, dog, cow, mouse, rat, chicken, and frog. 2 alternatively spliced human isoforms have been reported. The 183-amino acid protein has a reported mass of 20,002 daltons. The cellular localization is predicted to be membrane-associated. C12orf59 might act as a potential oncogenic protein in gastric cancer (GC). Researchers propose that the decreased C12orf59 expression status is a prognostic biomarker of ccRCC and cooperates with the loss of von Hippel-Lindau (VHL) all the while promoting renal carcinogenesis. 192 organisms have orthologs with human gene TMEM52B.

    分子量

    24 kDa

    基因ID

    120939
You are here:
Chat with us!