TMEM52B 抗体 (AA 22-183)
Quick Overview for TMEM52B 抗体 (AA 22-183) (ABIN7600679)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-183
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原理
- Anti-TMEM52B Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TMEM52B Antibody Picoband® (ABIN7600679). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TMEM52B recombinant protein (Position: T22-N183).
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亚型
- IgG
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anti-Transmembrane Protein 52B (TMEM52B) (AA 61-183) antibody
TMEM52B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 52B (TMEM52B) (C-Term) antibodyTMEM52B 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Zhang JX, et al. (2019) A positive feedback loop consisting of c12orf59/nf-κb/cdh11 promotes gastric cancer invasion and metastasis. J Exp Clin Cancer Res 38 (1): 164. 2. Xie J, et al. (2016) Down-regulation of c12orf59 is associated with a poor prognosis and vhl mutations in renal cell carcinoma. Oncotarget 7 (6): 6824-6834. 3. Clark HF, et al. (2003) The secreted protein discovery initiative (spdi), a large-scale effort to identify novel human secreted and transmembrane proteins: A bioinformatics assessment. Genome Res 13 (10): 2265-2270. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TMEM52B (Transmembrane Protein 52B (TMEM52B))
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别名
- TMEM52B
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背景
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Synonyms: Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1, PYROXD1
Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Background: TMEM52B (Transmembrane Protein 52B, also known as C12orf59) is a Protein Coding gene. The TMEM52B gene, located on 12p13.2, is conserved in chimpanzee, dog, cow, mouse, rat, chicken, and frog. 2 alternatively spliced human isoforms have been reported. The 183-amino acid protein has a reported mass of 20,002 daltons. The cellular localization is predicted to be membrane-associated. C12orf59 might act as a potential oncogenic protein in gastric cancer (GC). Researchers propose that the decreased C12orf59 expression status is a prognostic biomarker of ccRCC and cooperates with the loss of von Hippel-Lindau (VHL) all the while promoting renal carcinogenesis. 192 organisms have orthologs with human gene TMEM52B.
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分子量
- 24 kDa
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基因ID
- 120939
抗原
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