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RAB23 抗体 (AA 22-168)

This anti-RAB23 antibody is a 兔 多克隆 antibody detecting RAB23 in WB, ELISA 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7600675
发货至: 中国

Quick Overview for RAB23 抗体 (AA 22-168) (ABIN7600675)

抗原

See all RAB23 抗体
RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

适用

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人, 小鼠, 大鼠

宿主

  • 33
  • 9
  • 1

克隆类型

  • 36
  • 7
多克隆

标记

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This RAB23 antibody is un-conjugated

应用范围

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  • 22
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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 5
    • 4
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    • 1
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    • 1
    • 1
    AA 22-168

    原理

    Anti-RAB23 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-RAB23 Antibody Picoband® (ABIN7600675). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human RAB23 recombinant protein (Position: K22-K168).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Alessandri, J.-L., Dagoneau, N., Laville, J.-M., Baruteau, J., Hebert, J.-C., Cormier-Daire, V. RAB23 mutation in a large family from Comoros Islands with Carpenter syndrome. Am. J. Med. Genet. 152A: 982-986, 2010. 2. Eggenschwiler, J. T., Espinoza, E., Anderson, K. V. Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway. Nature 412: 194-198, 2001. 3. Gunther, T., Struwe, M., Aguzzi, A., Schughart, K. open brain, a new mouse mutant with severe neural tube defects, shows altered gene expression patterns in the developing spinal cord. Development 120: 3119-3130, 1994.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

    别名

    RAB23

    背景

    Synonyms: Thioredoxin, mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2

    Tissue Specificity: Widely expressed in adult (at protein level) and fetal tissues.

    Background: Ras-related protein Rab-23 is a protein that in humans is encoded by the RAB23 gene. This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants.

    分子量

    27 kDa

    基因ID

    51715

    途径

    Tube Formation
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