电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SOD3 抗体 (AA 22-161)

This anti-SOD3 antibody is a 兔 多克隆 antibody detecting SOD3 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7600674
发货至: 中国

Quick Overview for SOD3 抗体 (AA 22-161) (ABIN7600674)

抗原

See all SOD3 抗体
SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))

适用

  • 53
  • 21
  • 8
  • 5
人, 小鼠, 大鼠

宿主

  • 51
  • 25
  • 2
  • 2

克隆类型

  • 55
  • 25
多克隆

标记

  • 51
  • 11
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
This SOD3 antibody is un-conjugated

应用范围

  • 67
  • 48
  • 37
  • 31
  • 14
  • 14
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-161

    原理

    Anti-Superoxide Dismutase 3/EC-SOD/SOD3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Superoxide Dismutase 3/EC-SOD/SOD3 Antibody Picoband® (ABIN7600674). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Superoxide Dismutase 3/EC-SOD/SOD3 recombinant protein (Position: E22-A161).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Folz, R. J., Crapo, J. D.Extracellular superoxide dismutase (SOD3): tissue-specific expression, genomic characterization, and computer-assisted sequence analysis of the human EC SOD gene.Genomics 22: 162-171, 1994. 2. Hjalmarsson, K., Marklund, S. L., Engstrom, A., Edlund, T.Isolation and sequence of complementary DNA encoding human extracellular superoxide dismutase.Proc. Nat. Acad. Sci. 84: 6340-6344, 1987. 3. Stern, L.F., Chapman, N. H., Wijsman, E. M., Altherr, M. R., Rosen, D. R.Assignment of SOD3 to human chromosome band 4p15.3-p15.1 with somatic cell and radiation hybrid mapping, linkage mapping, and fluorescent in-situ hybridization.Cytogenet. Genome Res. 101: 178 only, 2003.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))

    别名

    SOD3

    背景

    Synonyms: Extracellular superoxide dismutase [Cu-Zn], EC-SOD, 1.15.1.1, SOD3

    Tissue Specificity: Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.

    Background: SOD3 (SUPEROXIDE DISMUTASE 3), also called SUPEROXIDE DISMUTASE, EXTRACELLULAR, EC-SOD, and Cu-Zn, is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. Hendrickson et al. (1990) mapped the SOD3 gene to 4pter-q21 by a study of somatic cell hybrids. Stern et al. (2003) narrowed the assignment to 4p15.3-p15.1 by somatic cell and radiation hybrid analysis, linkage mapping, and FISH. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.

    分子量

    32 kDa

    基因ID

    6649

    UniProt

    P08294
You are here:
Chat with us!