Cytokeratin 1 抗体 (AA 215-431)
Quick Overview for Cytokeratin 1 抗体 (AA 215-431) (ABIN7600651)
抗原
See all Cytokeratin 1 (KRT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 215-431
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原理
- Anti-Cytokeratin 1/KRT1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Cytokeratin 1/KRT1 Antibody Picoband® (ABIN7600651). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Cytokeratin 1/KRT1 recombinant protein (Position: L215-Q431).
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亚型
- IgG
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anti-Keratin 1 (KRT1) (AA 141-240) antibody
KRT1 适用: 人, 大鼠, 小鼠, Cow WB, FACS, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) antibodyKRT1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Keratin 1 (KRT1) (AA 101-200) antibodyKRT1 适用: 人, 小鼠, 马 WB, FACS, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) (AA 487-644) antibodyKRT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) (AA 189-497) antibodyKRT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) (AA 267-438) antibodyKRT1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 1 (KRT1) (C-Term) antibodyKRT1 适用: 人, 大鼠 IHC, StM 宿主: 小鼠 Monoclonal LHK1 unconjugated
anti-Keratin 1 (KRT1) (AA 415-443) antibodyKRT1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18411 unconjugated
anti-Keratin 1 (KRT1) antibodyKRT1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Monoclonal 1C2 unconjugated
anti-Keratin 1 (KRT1) (AA 387-496) antibodyKRT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chipev, C. C., Korge, B. P., Markova, N., Bale, S. J., DiGiovanna, J. J., Compton, J. G., Steinert, P. M. A leucine-to-proline mutation in the H1 subdomain of keratin 1 causes epidermolytic hyperkeratosis. Cell 70: 821-828, 1992. 2. Compton, J. G. Epidermal disease: faulty keratin filaments take their toll. Nature Genet. 6: 6-7, 1994. 3. Compton, J. G., DiGiovanna, J. J., Santucci, S. K., Kearns, K. S., Amos, C. I., Abangan, D. L., Korge, B. P., McBride, O. W., Steinert, P. M., Bale, S. J. Linkage of epidermolytic hyperkeratosis to the type II keratin gene cluster on chromosome 12q. Nature Genet. 1: 301-305, 1992. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
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别名
- KRT1
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背景
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Synonyms: Pituitary homeobox 2, ALL1-responsive protein ARP1, Homeobox protein PITX2, Paired-like homeodomain transcription factor 2, RIEG bicoid-related homeobox transcription factor, Solurshin, PITX2, ARP1, RGS, RIEG, RIEG1
Tissue Specificity: Isoform 1 is expressed in neurons of the cerebellum and hippocampus. Isoform 2 is expressed in thymus, spleen and lung.
Background: Keratin 1 is a Type II intermediate filament (IFs) of the intracytoplasmatic cytoskeleton. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
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分子量
- 66 kDa
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基因ID
- 3848
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UniProt
- P04264
抗原
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