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GPR50 抗体 (AA 214-471)

This anti-GPR50 antibody is a 兔 多克隆 antibody detecting GPR50 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7600650
发货至: 中国

Quick Overview for GPR50 抗体 (AA 214-471) (ABIN7600650)

抗原

See all GPR50 抗体
GPR50 (G Protein-Coupled Receptor 50 (GPR50))

适用

  • 30
  • 6
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人, 小鼠

宿主

  • 28
  • 3

克隆类型

  • 30
  • 1
多克隆

标记

  • 26
  • 1
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  • 1
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  • 1
This GPR50 antibody is un-conjugated

应用范围

  • 20
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Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 5
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    • 1
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    • 1
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    • 1
    • 1
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    AA 214-471

    原理

    Anti-GPR50 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-GPR50 Antibody Picoband® (ABIN7600650). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GPR50 recombinant protein (Position: K214-S471).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. Gubitz, A. K., Reppert, S. M. Assignment of the melatonin-related receptor to human chromosome X (GPR50) and mouse chromosome X (Gpr50). Genomics 55: 248-251, 1999. 2. Levoye, A., Dam, J., Ayoub, M. A., Guillaume, J.-L., Couturier, C., Delagrange, P., Jockers, R. The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization. EMBO J. 25: 3012-3023, 2006. 3. Reppert, S. M., Weaver, D. R., Ebisawa, T., Mahle, C. D., Kolakowski, L. F., Jr. Cloning of a melatonin-related receptor from human pituitary. FEBS Lett. 386: 219-224, 1996.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    GPR50 (G Protein-Coupled Receptor 50 (GPR50))

    别名

    GPR50

    背景

    Synonyms: Protein SOX-15, Protein SOX-12, Protein SOX-20, SOX15, SOX12, SOX20, SOX26, SOX27

    Tissue Specificity: Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

    Background: G protein-coupled receptor 50 is a protein which in humans is encoded by the GPR50 gene. This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women.

    分子量

    67 kDa

    基因ID

    9248

    UniProt

    Q13585
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