GMP Synthase 抗体 (AA 21-671)
Quick Overview for GMP Synthase 抗体 (AA 21-671) (ABIN7600629)
抗原
See all GMP Synthase (GMPS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-671
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原理
- Anti-GMPS Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GMPS Antibody Picoband® (ABIN7600629). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GMPS recombinant protein (Position: H21-K671).
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亚型
- IgG
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anti-Guanine Monophosphate Synthetase (GMPS) (AA 108-215) antibody
GMPS 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Guanine Monophosphate Synthetase (GMPS) (AA 108-216) antibodyGMPS 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Guanine Monophosphate Synthetase (GMPS) (AA 394-693) antibodyGMPS 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Guanine Monophosphate Synthetase (GMPS) (AA 108-215) antibodyGMPS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Guanine Monophosphate Synthetase (GMPS) (AA 1-693) antibodyGMPS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Guanine Monophosphate Synthetase (GMPS) (AA 1-693) antibodyGMPS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Guanine Monophosphate Synthetase (GMPS) (AA 394-693) antibodyGMPS 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Guanine Monophosphate Synthetase (GMPS) (AA 296-325) antibodyGMPS 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20727 unconjugated
anti-Guanine Monophosphate Synthetase (GMPS) (AA 602-630), (C-Term) antibodyGMPS 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20728 unconjugated
anti-Guanine Monophosphate Synthetase (GMPS) antibodyGMPS 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hirst, M., Haliday, E., Nakamura, J., Lou, L. Human GMP synthetase: protein purification, cloning, and functional expression of cDNA. J. Biol. Chem. 269: 23830-23837, 1994. 2. Pegram, L. D., Megonigal, M. D., Lange, B. J., Nowell, P. C., Rowley, J. D., Rappaport, E. F., Felix, C. A. t(3,11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (guanosine 5-prime monophosphate synthetase) gene. Blood 96: 4360-4362, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))
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别名
- GMPS
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背景
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Synonyms: DNA replication licensing factor MCM5, CDC46 homolog, P1-CDC46, MCM5, CDC46
Tissue Specificity: Ubiquitous.
Background: Guanosine monophosphate synthetase, also known as GMPS is an enzyme that converts xanthosine monophosphate to guanosine monophosphate. In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
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分子量
- 77 kDa
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基因ID
- 8833
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UniProt
- P49915
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途径
- Ribonucleoside Biosynthetic Process
抗原
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