MRPS22 抗体 (AA 21-329)
Quick Overview for MRPS22 抗体 (AA 21-329) (ABIN7600613)
抗原
See all MRPS22 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-329
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原理
- Anti-MRPS22 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MRPS22 Antibody Picoband® (ABIN7600613). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MRPS22 recombinant protein (Position: E21-K329).
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亚型
- IgG
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anti-Mitochondrial Ribosomal Protein S22 (MRPS22) (AA 1-360) antibody
MRPS22 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Ribosomal Protein S22 (MRPS22) (AA 1-360) antibodyMRPS22 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Ribosomal Protein S22 (MRPS22) (Internal Region) antibodyMRPS22 适用: 人, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Ribosomal Protein S22 (MRPS22) (AA 1-360) antibodyMRPS22 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Mitochondrial Ribosomal Protein S22 (MRPS22) antibodyMRPS22 适用: 人, 小鼠, 猴, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Ribosomal Protein S22 (MRPS22) antibodyMRPS22 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Ribosomal Protein S22 (MRPS22) (C-Term) antibodyMRPS22 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Ribosomal Protein S22 (MRPS22) (AA 231-280) antibodyMRPS22 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, A., Tiosano, D., Guran, T., Baris, H. N., Bayram, Y., Mory, A., Shapiro-Kulnane, L., Hodges, C. A., Akdemir, Z. C., Turan, S., Jhangiani, S. N., van den Akker, F., Hoppel, C. L., Salz, H. K., Lupski, J. R., Buchner, D. A. Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency. Hum. Molec. Genet. 27: 1913-1926, 2018. 2. Crisponi, L., Deiana, M., Loi, A., Chiappe, F., Uda, M., Amati, P., Bisceglia, L., Zelante, L., Nagaraja, R., Porcu, S., Ristaldi, M. S., Marzella, R., and 10 others. The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome. Nature Genet. 27: 159-166, 2001. 3. Crisponi, L., Uda, M., Deiana, M., Loi, A., Nagaraja, R., Chiappe, F., Schlessinger, D., Cao, A., Pilia, G. FOXL2 inactivation by a translocation 171 kb away: analysis of 500 kb of chromosome 3 for candidate long-range regulatory sequences. Genomics 83: 757-764, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MRPS22 (Mitochondrial Ribosomal Protein S22 (MRPS22))
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别名
- MRPS22
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背景
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Synonyms: Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA
Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.
Background: 28S ribosomal protein S22, mitochondrial is a protein that in humans is encoded by the MRPS22 gene. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite ion from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq.
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分子量
- 38 kDa
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基因ID
- 56945
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UniProt
- P82650
抗原
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