SCO1 抗体 (AA 21-301)
Quick Overview for SCO1 抗体 (AA 21-301) (ABIN7600609)
抗原
See all SCO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-301
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原理
- Anti-SCO1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SCO1 Antibody Picoband® (ABIN7600609). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SCO1 recombinant protein (Position: R21-S301).
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亚型
- IgG
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anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (AA 1-301) antibody
SCO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (AA 1-160) antibodySCO1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (AA 125-158) antibodySCO1 适用: 人 WB 宿主: 兔 Polyclonal RB48404 unconjugated
anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (AA 29-176) antibodySCO1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (AA 202-301) antibodySCO1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (AA 107-156) antibodySCO1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-SCO1 Cytochrome C Oxidase Assembly Protein (SCO1) (Center) antibodySCO1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Horvath, R., Lochmuller, H., Stucka, R., Yao, J., Shoubridge, E. A., Kim, S.-H., Gerbitz, K.-D., Jaksch, M. Characterization of human SCO1 and COX17 genes in mitochondrial cytochrome-c-oxidase deficiency. Biochem. Biophys. Res. Commun. 276: 530-533, 2000. 2. Leary, S. C., Cobine, P. A., Nishimura, T., Verdijk, R. M., de Krijger, R., de Coo, R., Tarnopolsky, M. A., Winge, D. R., Shoubridge, E. A. Cox19 mediates the transduction of a mitochondrial redox signal from SCO1 that regulates ATP7A-mediated cellular copper efflux. Molec. Biol. Cell 24: 683-691, 2013. 3. Leary, S. C., Kaufman, B. A., Pellecchia, G., Guercin, G.-H., Mattman, A., Jaksch, M., Shoubridge, E. A. Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase. Hum. Molec. Genet. 13: 1839-1848, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SCO1 (SCO1 Cytochrome C Oxidase Assembly Protein (SCO1))
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别名
- SCO1
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背景
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Synonyms: Peroxisome proliferator-activated receptor gamma coactivator 1-beta, PGC-1-beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PGC-1-related estrogen receptor alpha coactivator, PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Tissue Specificity: Preferentially expressed in melanocytes.
Background: Protein SCO1 homolog, mitochondrial, also known as SCO1, cytochrome c oxidase assembly protein, is a protein that in humans is encoded by the SCO1 gene. Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene.
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分子量
- 30 kDa
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基因ID
- 6341
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UniProt
- O75880
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途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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