ORAI2 抗体 (AA 21-254)
Quick Overview for ORAI2 抗体 (AA 21-254) (ABIN7600605)
抗原
See all ORAI2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-254
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原理
- Anti-Orai2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Orai2 Antibody Picoband® (ABIN7600605). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Orai2 recombinant protein (Position: H21-L254).
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亚型
- IgG
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anti-ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) (AA 146-195) antibody
ORAI2 适用: 人, Cow, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) (C-Term) antibodyORAI2 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2) (AA 16-32), (Intracellular) antibodyORAI2 适用: 小鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Feske, S., Gwack, Y., Prakriya, M., Srikanth, S., Puppel, S.-H., Tanasa, B., Hogan, P. G., Lewis, R. S., Daly, M., Rao, A. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441: 179-185, 2006. 2. Mercer, J. C., DeHaven, W. I., Smyth, J. T., Wedel, B., Boyles, R. R., Bird, G. S., Putney, J. W., Jr. Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. J. Biol. Chem. 281: 24979-24990, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))
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别名
- ORAI2
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背景
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Synonyms: BAG family molecular chaperone regulator 5,BAG-5,Bcl-2-associated athanogene 5,BAG5,KIAA0873,
Tissue Specificity: Expressed in all tissues examined with lower levels in brain and testis.
Background: Protein orai-2 is a protein that in humans is encoded by the ORAI2 gene. Orai2 transcripts are predominantly expressed in kidney, lung, and spleen, and it appears that Orai2 is the only Orai isoform with multiple transcripts. Co-expresssion of Orai2 and STIM1 was shown to produce currents that appear similar but smaller than those produced by co-expression of Orai1 and STIM1.
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分子量
- 39 kDa
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基因ID
- 80228
抗原
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