RAB7A 抗体 (AA 21-177)
Quick Overview for RAB7A 抗体 (AA 21-177) (ABIN7600597)
抗原
See all RAB7A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-177
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原理
- Anti-RAB7/RAB7A Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RAB7/RAB7A Antibody Picoband® (ABIN7600597). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RAB7/RAB7A recombinant protein (Position: K21-E177).
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亚型
- IgG
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anti-RAB7A, Member RAS Oncogene Family (RAB7A) (C-Term) antibody
RAB7A 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, 猴, 兔, Cat, 驴, 山羊, 豚鼠, Hamster, 马, Pig, Avian, 绵羊 WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 176-204), (C-Term) antibodyRAB7A 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21394 unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 101-207) antibodyRAB7A 适用: 人, 小鼠 WB, ELISA, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 176-204) antibodyRAB7A 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 110-177) antibodyRAB7A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) antibodyRAB7A 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 1-207) antibodyRAB7A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (C-Term) antibodyRAB7A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (C-Term) antibodyRAB7A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) antibodyRAB7A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: RAB7A RAB7A, member RAS oncogene family". 2. Davies JP, Cotter PD, Ioannou YA (Apr 1997). "Cloning and mapping of human Rab7 and Rab9 cDNA sequences and identification of a Rab9 pseudogene". Genomics 41 (1): 131-4. 3. Kashuba VI, Gizatullin RZ, Protopopov AI, Allikmets R, Korolev S, Li J, Boldog F, Tory K, Zabarovska V, Marcsek Z, Sumegi J, Klein G, Zabarovsky ER, Kisselev L (Dec 1997). "NotI linking/jumping clones of human chromosome 3: mapping of the TFRC, RAB7 and HAUSP genes to regions rearranged in leukemia and deleted in solid tumors". FEBS Letters 419 (2-3): 181-5. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
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别名
- RAB7A
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背景
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Synonyms: Nuclear pore complex protein Nup214, 214 kDa nucleoporin, Nucleoporin Nup214, Protein CAN, NUP214, CAIN, CAN, KIAA0023
Tissue Specificity: Expressed in thymus, spleen, bone marrow, kidney, brain and testis, but hardly in all other tissues or in whole embryos during development.
Background: Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. RAB7A functions as a key regulator in endo-lysosomal trafficking, governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end ed endosomal migration and positions, and endosome-lysosome transport through different protein-protein interaction cascades. Furthermore, RAB7A is involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes through modulation of SOX10 and the oncogene MYC. Mutations in the lysosomal pathway result in tumor progression in melanoma cells.
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分子量
- 23 kDa
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基因ID
- 7879
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UniProt
- P51149
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途径
- EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
抗原
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