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beta-2 Microglobulin 抗体 (AA 21-119)

This anti-beta-2 Microglobulin antibody is a 兔 多克隆 antibody detecting beta-2 Microglobulin in WB, FACS, ELISA, IF 和 ICC. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7600594
发货至: 中国

Quick Overview for beta-2 Microglobulin 抗体 (AA 21-119) (ABIN7600594)

抗原

See all beta-2 Microglobulin (B2M) 抗体
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This beta-2 Microglobulin antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
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    AA 21-119

    原理

    Anti-beta 2 Microglobulin/B2m Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-beta 2 Microglobulin/B2m Antibody Picoband® (ABIN7600594). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived rat beta 2 Microglobulin/B2m recombinant protein (Position: I21-M119).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Rat
    ELISA, 0.1-0.5 μg/mL,
    1. Güssow D, Rein R, Ginjaar I, Hochstenbach F, Seemann G, Kottman A, Ploegh HL (1 November 1987). "The human beta 2-microglobulin gene. Primary structure and definition of the transcriptional unit". J. Immunol. 139 (9): 3132-8. 2. Munshi NC, Longo DL, Anderson KC (2011). "Chapter 111: Plasma Cell Disorders". In Loscalzo J, Longo DL, Fauci AS, Dennis LK, Hauser SL. Harrison's Principles of Internal Medicine (18th ed.). McGraw-Hill Professional. pp. 936-44. 3. Pignone M, Nicoll D, McPhee SJ (2004). Pocket guide to diagnostic tests (4th ed.). New York: McGraw-Hill. p. 191.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    别名

    B2m

    背景

    Synonyms: Beta-2-microglobulin, B2m

    Tissue Specificity: Detected in lung, spleen, uterus, vagina and epididymis. .

    Background: Beta-2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on all nucleated cells (excludes red blood cells). In humans, the beta-2-microglobulin protein is encoded by the B2M gene. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

    分子量

    13 kDa

    基因ID

    12010

    UniProt

    P01887

    途径

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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