LY6E 抗体 (AA 21-101)
Quick Overview for LY6E 抗体 (AA 21-101) (ABIN7600591)
抗原
See all LY6E 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 21-101
-
原理
- Anti-LY6E/SCA-2 Antibody Picoband®
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
产品特性
- Anti-LY6E/SCA-2 Antibody Picoband® (ABIN7600591). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human LY6E/SCA-2 recombinant protein (Position: L21-S101).
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Mao, M., Yu, M., Tong, J.-H., Ye, J., Zhu, J., Huang, Q.-H., Fu, G., Yu, L., Zhao, S.-Y., Waxman, S., Lanotte, M., Wang, Z.-Y., Tan, J.-Z., Chan, S.-J., Chen, Z. RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell. Proc. Nat. Acad. Sci. 93: 5910-5914, 1996. 2. Shan, X., Bourdeau, A., Rhoton, A., Wells, D. E., Cohen, E. H., Landgraf, B. E., Palfree, R. G. E. Characterization and mapping to human chromosome 8q24.3 of Ly-6-related gene 9804 encoding an apparent homologue of mouse TSA-1. J. Immun. 160: 197-208, 1998. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- LY6E (Lymphocyte Antigen 6 Complex, Locus E (LY6E))
-
别名
- LY6E
-
背景
-
Synonyms: Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20, TRF-proximal protein homolog, hTRFP, MED20, TRFP,
Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.
Background: Lymphocyte antigen 6E is a protein that in humans is encoded by the LY6E gene. Increased expression of Ly6E is associated with poor survival outcome in multiple malignancies as determined by a survey of more than 130 published clinical studies of gene expression studies on cancer tissue samples and adjacent normal tissues. Ly6E is associated with drug resistance and tumor immune escape in breast cancer. Further research is required to validate Ly6E for translation research.
-
分子量
- 14 kDa
-
基因ID
- 4061
-
UniProt
- Q16553
-
途径
- Hormone Transport
抗原
-