SCYL2 抗体 (AA 208-909)
Quick Overview for SCYL2 抗体 (AA 208-909) (ABIN7600588)
抗原
See all SCYL2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 208-909
-
原理
- Anti-SCYL2 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-SCYL2 Antibody Picoband® (ABIN7600588). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SCYL2 recombinant protein (Position: E208-Q909).
-
亚型
- IgG
-
-
anti-SCY1-Like 2 (SCYL2) (AA 1-300) antibody
SCYL2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SCY1-Like 2 (SCYL2) (AA 1-929) antibodySCYL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SCY1-Like 2 (SCYL2) antibodySCYL2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SCY1-Like 2 (SCYL2) antibodySCYL2 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SCY1-Like 2 (SCYL2) (AA 585-613) antibodySCYL2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SCY1-Like 2 (SCYL2) (AA 643-672), (C-Term) antibodySCYL2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Conner, S. D., Schmid, S. L. CVAK104 is a novel poly(L)-lysine-stimulated kinase that targets the beta-2-subunit of AP2. J. Biol. Chem. 280: 21539-21544, 2005. 2. Gingras, S., Earls, L. R., Howell, S., Smeyne, R. J., Zakharenko, S. S., Pelletier, S. SCYL2 protects CA3 pyramidal neurons from excitotoxicity during functional maturation of the mouse hippocampus. J. Neurosci. 35: 10510-10522, 2015. 3. Gross, M. B. Personal Communication. Baltimore, Md. 5/15/2015. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- SCYL2 (SCY1-Like 2 (SCYL2))
-
别名
- SCYL2
-
背景
-
Synonyms: Gap junction gamma-1 protein,Connexin-45,Cx45,Gap junction alpha-7 protein,GJC1,GJA7,
Tissue Specificity: Ubiquitously expressed.
Background: SCY1-like protein 2 is a protein that in humans is encoded by the SCYL2 gene. The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene.
-
分子量
- 104 kDa
-
基因ID
- 55681
-
UniProt
- Q6P3W7
抗原
-
